动物血源抗菌肽的研究进展及应用  

Progress and Application of Animal Blood-derived Antibacterial Peptides

作　　者：应晓彩 刘磊[1] 裴志花[1] 王开[1] YING Xiai-cai;LIU Lei;PEI Zhi-hua;WANG Kai(College of Animal Science and Technology,Jilin Agricultural University,Changchun,Jilin,130118,China)

机构地区：[1]吉林农业大学动物科学技术学院,吉林长春130118

出　　处：《动物医学进展》2020年第9期111-114,共4页Progress In Veterinary Medicine

基　　金：国家自然科学青年基金项目(31502021,31572574);吉林省科技发展计划项目(20170101021JC);吉林省科技攻关项目(20160204002NY)。

摘　　要：抗菌肽是一种小分子多肽,可抵抗外源性病原微生物的侵袭。动物血液是畜禽屠宰加工的主要副产品,具有较高的营养价值,近年来发现血液中不但富含蛋白质,还存在多种生物活性肽,如免疫增强肽、抗氧化肽、抗肿瘤肽和抗菌肽等,具有极为广阔的开发和应用前景。论文综述了动物血源性抗菌肽的分类、提取方法和临床应用,并对其应用前景进行了展望,为抗菌肽的应用和开发提供理论依据。Antimicrobial peptides are small molecular polypeptides that can resist the invasion of various exogenous pathogenic microorganisms.Animal blood is the main by-product of slaughtering and processing of livestock and poultry.It has high nutritional value.In recent years,it has been found that blood is not only rich in protein,but also contains a variety of bioactive peptides,such as immunopotentiator,antioxidant,antineoplastic and antimicrobial peptides,which have very broad prospects for development and application.In this paper,the classification,extraction methods and clinical application of animal blood-derived antimicrobial peptides were reviewed,and their application prospects were prospected.It provided a theoretical basis for the application and development of antimicrobial peptides.

关 键 词：抗菌肽 动物血源 应用 

分 类 号：S852.4[农业科学—基础兽医学]