中山市育龄期多囊卵巢综合征患者管理体系的建立对妊娠结局的影响  

Effect of management system on pregnancy outcome in patients with polycystic ovary syndrome of childbearing age in Zhongshan City

作　　者：吴日然[1] 李洁亮 李庆妮 杜静[1] 卢惠燕 许婷 廖月婵[1] 柯玩娜[1] 吴嘉齐[1] 林秀峰[1] Wu Riran;Li Jieliang;Li Qingni;Du Jing;Lu Huiyan;Xu Ting;Liao Yuechan;Ke Wanna;Wu Jiaqi;Lin Xiufeng(Reproductive Center of Zhongshan Boai Hospital,Zhongshan 528400,China)

机构地区：[1]中山市博爱医院生殖中心,528400

出　　处：《中华生殖与避孕杂志》2020年第7期579-583,共5页Chinese Journal of Reproduction and Contraception

基　　金：中山市重大科技项目(2016B1007)。

摘　　要：目的探讨育龄期多囊卵巢综合征(PCOS)患者管理体系的建立对妊娠结局的影响。方法回顾性分析2016年6月至2018年5月期间在中山市博爱医院生殖中心就诊的1203名20~45岁多囊卵巢综合征(PCOS)患者,愿意纳入长期管理系统的有755名(研究组),进行基础血压及体质量控制、血清指标监测,建立PCOS管理微信平台等方法对其进行科普教育。同期448位PCOS患者未纳入长期管理系统(对照组),进行妊娠情况的追踪。结果研究组总的妊娠率为25.74%(148/575),高于对照组的18.13%(62/342),差异有统计学意义(P=0.010)。研究组总流产率为14.19%(21/148),低于对照组的22.58%(14/62),但差异无统计学意义(P=0.199)。结论对育龄期PCOS患者进行综合管理,提高公众对PCOS作为慢性病的认知和接受度,提高PCOS患者的依从性,能改善PCOS患者妊娠结局。Objective To investigate the effect of management system on pregnancy outcome in patients with polycystic ovary syndrome(PCOS)of childbearing age.Methods A total of 1203 patients with PCOS aged 20-45 years were collected in Reproductive Center of Zhongshan Boai Hospital from June 2016 to May 2018.Totally 755 who would like to be included in the long term management system were collected as study group and received basic blood pressure and weight control and serum monitoring,scientific education was performed through WeChat platform established for PCOS management and other methods.Other 448 patients with PCOS were not included in the long-term management system(control group),and their pregnancy outcomes were followed up.Results The total pregnancy rate of study group was higher than that of control group(25.74%vs.18.13%,P=0.010),and the total abortion rate of study group was lower than that of control group(14.19%vs.22.58%,P=0.199).Conclusion Comprehensive management of PCOS patients of childbearing age can improve the public's cognition and acceptance of PCOS as a chronic disease,improve the compliance and pregnancy outcome of PCOS patients.

关 键 词：妊娠 多囊卵巢综合征 流产 生殖 

分 类 号：R711.75[医药卫生—妇产科学]