网状Meta分析证据质量分级:GRADE方法学前沿与进展  

Advance in the GRADE approach to rate the quality of evidence from a network metaanalysis

作　　者：王琪 王建成[2] 潘蓓 张迁[3] 周奇[4,5] 田金徽 陈耀龙[4,5] 杨克虎 吴大嵘[6] 郭新峰 杨丽虹[6] Gordon Guyatt 葛龙[1,5] WANG Qi;WANG Jiancheng;PAN Bei;ZHANG Qian;ZHOU Qi;TIAN Jinhui;CHEN Yaolong;YANG Kehu;WU Darong;GUO Xinfeng;YANG Lihong;Gordon Guyatt;GE Long(Evidence-Based Social Science Research Center,School of Public Health,Lanzhou University,Lanzhou 730000,P.R.China;Gansu Provincial Hospital,Lanzhou 730000,P.R.China;School of Nursing,Lanzhou University,Lanzhou 730000,P.R.China;Evidence-Based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Lanzhou 730000,P.R.China;Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province,Lanzhou 730000,P.R.China;The Second Affiliated Hospital of Guangzhou University of Chinese Medicine/Guangdong Provincial Hospital of Chinese Medicine,Guangzhou 510120,P.R.China;Department of Health Research Methods,Evidence and Impact,McMaster University,Hamilton L8S4L8,Canada)

机构地区：[1]兰州大学公共卫生学院循证社会科学研究中心,兰州730000 [2]甘肃省人民医院,兰州730000 [3]兰州大学护理学院,兰州730000 [4]兰州大学基础医学院循证医学中心,兰州730000 [5]甘肃省循证医学与临床转化重点实验室,兰州730000 [6]广州中医药大学第二附属医院/广东省中医院,广州510120 [7]麦克马斯特大学卫生研究方法、证据和影响力系,加拿大哈密尔顿L8S4L8

出　　处：《中国循证医学杂志》2020年第8期979-985,共7页Chinese Journal of Evidence-based Medicine

基　　金：国家重点研发计划资助项目(编号:2019YFC1709805);甘肃省人民医院2019年国家级科研项目培育计划一般项目(编号:19SYPYB-18);兰州市城关区人才创新创业类项目(编号:2019RCCX0011)。

摘　　要：2014年,GRADE工作组在英国医学会期刊BMJ首次介绍了GRADE方法用于网状Meta分析证据质量分级的应用指南。GRADE工作组认为在进行网状Meta分析证据分级时,需要单独对直接证据、间接证据和网状Meta分析证据质量进行分级。近年来,GRADE工作组发表了系列论文,对该方法进行了进一步的完善和补充。本文旨在对GRADE方法用于网状Meta分析证据质量分级的前沿和进展进行介绍,以期为相关研究人员提供参考。In 2014,the Grading of Recommendations Assessment,Development,and Evaluation(GRADE)working group published guidance in BMJ to evaluate the certainty of the evidence(confidence in evidence,quality of evidence)from network meta-analysis.GRADE working group suggested rating the certainty of direct evidence,indirect evidence,and network evidence,respectively.Recently,GRADE working group has published a series of papers to improve and supplement this approach.This paper introduces the frontiers and advancement of GRADE approach to rate the certainty of evidence from network meta-analysis.

关 键 词：网状Meta分析 GRADE方法 证据质量 

分 类 号：R311[医药卫生—基础医学]