喉咽癌手术患者术前贫血发生率及住院时长的影响因素分析  

Prevalence of preoperative anemia inpatients underwent laryngeal and pharyngeal cancer surgery:correlations with length of hospital stay

作　　者：孙芳 孙桂香 潘纪春 林洁 蔡晓谕 汪德清 SUN Fang;SUN Guixiang;PAN Jichun;LIN Jie;CAI Xiaoyu;WANG Deqing(Blood Transfusion Department,First Medical Center,General Hospital of PLA,Beijing 100853,China)

机构地区：[1]中国人民解放军总医院第一医学中心输血科,北京100853

出　　处：《中国输血杂志》2020年第5期487-490,共4页Chinese Journal of Blood Transfusion

基　　金：白求恩公益基金会课题(BQE-2018-SX-01);解放军总医院临床科研扶持基金课题(2018FC-WJFWZX-1-18)。

摘　　要：目的研究喉咽癌手术患者术前贫血情况,明确喉咽癌患者术前贫血对住院天数的影响。方法回顾性分析1 721例喉咽癌手术患者临床资料。结果喉咽癌患者术前贫血率17.37%,其中轻、中度,重度贫血的发生率分别为13.95%、3.43%。男性贫血患者242例,女性贫血患者57例,男女贫血发生率分别为15.48%、36.08%;各年龄段贫血与BMI(身体质量指数)贫血发生率有较大差异(P<0.05)。贫血患者平均住院天数与手术时间(19.37 d/130.59 min)较非贫血患者(15.26 d/113.68 min)延长(P<0.05)。对患者住院天数进行多因素logistic回归分析,患者术前贫血、WBC升高、ALB降低、凝血功能异常可导致患者住院天数延长。结论喉咽癌患者术前贫血发生率17.37%;不同性别、年龄、BMI的患者贫血发生率存在显著差异,术前贫血、WBC升高、ALB降低、凝血功能异常可使住院天数延长。Objective To study the status of preoperative anemia in a population of patients with laryngeal and pharyngeal cancer, so as to evaluate the possible correlations of anemia with length of hospitalization.Methods Retrospective analysis of a cohort of 1 721 patients with laryngeal and pharyngeal cancer admitted to our hospital was carried out. Results The preoperative anemia was observed in 17.37%(299/1 721)of patients with laryngeal and pharyngeal cancer, with mild/moderate anemia in 13.95% and severe anemia in 3.43%. Anemia was diagnosed in 242(15.48%) male patients and 57(36.08%) female patients. Age and BMI showed a significant association with the presence of anemia(P<0.05). The presence of anemia also correlated with a significantly longer hospital stay(19.37 d vs 15.26 d) and surgery duration(130.59 min vs 113.68 min) as compared with non-anemia patients(P<0.05). The multivariate logistic regression analysis revealed that the prolonged hospital stay was correlated with preoperative anemia, increased WBC, decreased ALB, abnormal coagulation function and other factors.Conclusion The preoperative anemia was observed in 17.37% of patients with laryngeal and pharyngeal cancer. Gender, age and BMI showed a significant association with the presence of anemia. Preoperative anemia, increased WBC, decreased ALB, and abnormal coagulation function also correlated with a significant longer hospital stay.

关 键 词：术前贫血 低蛋白 喉咽癌 输血 

分 类 号：R457.1[医药卫生—治疗学] R739.63[医药卫生—临床医学]