隔姜灸配合中药离子导入治疗原发性痛经疗效观察  

Clinical Observation of Ginger-Separated Moxibustion Combined with Iontophoresis of Traditional Chinese Medicine in Treatment of Primary Dysmenorrhea

作　　者：代凤超 于恬 郭洁丽 杜美容 刘秀敏 DAI Fengchao;YU Tian;GUO Jieli;DU Meirong;LIU Xiumin(Department of TCM,Maternal and Child Health Hospital of Tangshan,Tangshan 063000,Heibei,China)

机构地区：[1]唐山市妇幼保健院中医科,河北唐山063000

出　　处：《辽宁中医杂志》2020年第6期161-164,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：河北省中医药管理局科研计划项目(2019238)。

摘　　要：目的探讨隔姜灸配合中药离子导入治疗原发性痛经患者的临床疗效。方法选择2018年1月—2019年1月在该院就诊的252例原发性痛经患者作为研究对象,采用随机数字表法将患者随机分为西药组、艾灸组、离子组和联合组,每组63例。西药组给予布洛芬治疗,艾灸组给予隔姜灸治疗,离子组给予中药离子导入治疗,联合组给予隔姜灸联合中药离子导入治疗。观察治疗前、后血清雌二醇(E2)、孕酮(P)、前列腺素F2α(PGF2α)、β内啡肽(β-EP)水平和视觉模拟疼痛评分(VAS)。结果治疗后艾灸组、离子组E2水平均低于西药组,P水平高于西药组,差异均有统计学意义(P<0.05);治疗后联合组E2水平低于西药组、艾灸组和离子组,P水平高于西药组、艾灸组和离子组,差异均有统计学意义(P<0.05)。治疗后艾灸组、离子组PGF2α水平均低于西药组,β-EP水平高于西药组,差异均有统计学意义(P<0.05);治疗后联合组PGF2α水平低于西药组、艾灸组和离子组,β-EP水平高于西药组、艾灸组和离子组,差异均有统计学意义(P<0.05)。治疗后4组VAS与治疗前相比较均显著降低,且艾灸组、离子组与同期西药相比较均显著降低,联合组与同期西药组、艾灸组、离子组相比较均显著降低,差异均有统计学意义(P<0.05)。结论隔姜灸和中药离子导入具有协同作用,二者联合应用可进一步改善对原发性痛经的治疗效果,值得进一步研究探讨。Objective To investigate the clinical effect of ginger-separated moxibustion combined with iontophoresis of traditional Chinese medicine in the treatment of primary dysmenorrhea.Methods A total of 252 patients with primary dysmenorrhea who were treated in our hospital from January 2018 to January 2019 were selected as the research objects,and the patients were randomly divided into three groups: western medicine group,moxibustion group,ionic group and combined group,63 cases in each group.The serum levels of estradiol(E2),progesterone(P),prostaglandin F2 alpha(PGF2 alpha),beta-endorphin(beta-EP)and visual analogue pain score(VAS) were observed before and after treatment.Results After treatment,E2 level in moxibustion group and ionic group was lower than that in western medicine group,P level was higher than that in western medicine group,with statistical significance(P<0.05).E2 level in combined group was lower than that in western medicine group,moxibustion group and ionic group,P level was higher than that in western medicine group,moxibustion group and ionic group,with statistical significance(P<0.05).After treatment,the levels of PGF2 alpha in moxibustion group and ionic group were lower than those in western medicine group,and the levels of beta-EP were higher than those in western medicine group(P<0.05).After treatment,the levels of PGF2 alpha in combined group were lower than those in western medicine group,moxibustion group and ionic group,and the levels of beta-EP were higher than those in western medicine group,moxibustion group and ionic group,with statistical significance(P<0.05).After treatment,VAS in the four groups was significantly lower than that before treatment,and the VAS in the moxibustion group and the ionic group was significantly lower than that in the western medicine group.The VAS in the combined group was significantly lower than that in the western medicine group,the moxibustion group and the ionic group at the same time(P<0.05).Conclusion Ginger-separated moxibustion and iontophoresis

关 键 词：原发性痛经 隔姜灸 中药离子导入 临床疗效 

分 类 号：R711.51[医药卫生—妇产科学]