急性脑梗死患者及脑卒中高危人群中的脂蛋白a和中医体质辨识的研究  

Study of lipoprotein a and traditional Chinese medicine constitution identification in patients with acute cerebral infarction and high-risk of stroke

作　　者：邹志强 曾灶英 钟秀娴 蒙小文 ZOU Zhi-qiang;ZENG Zao-ying;ZHONG Xiu-xian(Nanhai District Eighth People's Hospital,Foshan 528223,China)

机构地区：[1]佛山市南海区第八人民医院,528223

出　　处：《中国实用医药》2020年第23期143-146,共4页China Practical Medicine

基　　金：佛山市自筹经费类科技计划项目(项目编号:2017AB000042)。

摘　　要：目的探究急性脑梗死患者及脑卒中高危人群中的脂蛋白a[Lp(a)]和中医体质辨识。方法选取40例急性脑梗死患者作为研究组,43例脑卒中高危人群作为对照组,37例健康人群作为健康对照组。采用免疫透射比浊法检测三组的脂蛋白a水平,采用2009年中华中医药学会出版的《中医体质分类与判定》量表测量三组的中医体质类型。比较三组脂蛋白a水平,观察三组的中医体质类型及脂蛋白a异常者中医体质类型分布情况。结果研究组脂蛋白a水平为(112.23±16.60)nmol/L,对照组脂蛋白a水平为(50.48±9.48)nmol/L,健康对照组脂蛋白a水平为(29.64±3.34)nmol/L;研究组脂蛋白a水平明显高于对照组和健康对照组,对照组高于健康对照组,差异均有统计学意义(P<0.05)。研究组中医体质类型主要分布于阴虚质27.50%(11/40)、气虚质17.50%(7/40)、平和质15.00%(6/40)、气郁质12.50%(5/40);对照组中医体质类型主要分布于平和质23.26%(10/43)、气郁质23.26%(10/43)、阴虚质20.93%(9/43)、痰湿质13.95%(6/43);健康对照组中医体质类型主要分布于平和质29.73%(11/37)、阴虚质27.03%(10/37)、湿热质13.51%(5/37)、血瘀质10.81%(4/37)、气虚质10.81%(4/37)。脂蛋白a异常患者的中医体质类型主要分布于阴虚质、气虚质、平和质、湿热质和痰湿质。结论高水平的脂蛋白a是患者出现急性脑梗死的重要因素之一,可通过脂蛋白a、中医体质监控和调节进行针对性的防治,从而降低急性脑梗死的发生率。Objective To investigate the correlation between lipoprotein a[Lp(a)]and traditional Chinese medicine constitution identification in patients with acute cerebral infarction and high-risk population of stroke.Methods There were 40 patients with acute cerebral infarction as research group,43 persons with high-risk of stroke as control group,and 37 health persons as healthy control group.The levels of lipoprotein a in three groups were detected by immunoturbidimetry,and the traditional Chinese medicine constitutions of the three groups were measured using the scale of"Classification and Judgment of traditional Chinese medicine Constitution"published by the Chinese Society of Chinese Medicine in 2009.The levels of lipoprotein a in the three groups were compared,and the traditional Chinese medicine constitution types of the three groups and the distribution of traditional Chinese medicine constitution types of patients with abnormal lipoprotein a were observed.Results The lipoprotein a level of the research group was(112.23±16.60)nmol/L,which was(50.48±9.48)nmol/L of the control group,and(29.64±3.34)nmol/L of the healthy control group.The lipoprotein a level of the research group was obviously higher than that of the control group and healthy control group,and the control group was higher than that of healthy control group,and the difference was statistically significant(P<0.05).The types of traditional Chinese medicine constitutions in the research group were mainly distributed in Yin deficiency 27.50%(11/40),Qi deficiency 17.50%(7/40),gentleness constitution 15.00%(6/40)and Qi depression 12.50%(5/40).The types of traditional Chinese medicine constitutions 13.95%(6/43)in the control group were mainly gentleness constitution 23.26%(10/43),Qi depression 23.26%(10/43),Yin deficiency 20.93%(9/43)and phlegm-dampness constitution.The types of traditional Chinese medicine constitutions in the healthy control group were mainly gentleness constitution 29.73%(11/37),Yin deficiency 27.03%(10/37),damp-heat constitution 13.51%

关 键 词：急性脑梗死 脑卒中高危人群 脂蛋白A 中医体质辨识 

分 类 号：R277.7[医药卫生—中医学]