非低血糖状态下饥饿感对2型糖尿病患者睡眠质量、生活质量的影响  

Effects of Hunger on Sleep and Life Quality of T2DM Patients Under Non-hypoglycemia State

作　　者：付利丽 郭强 喻国[1] 周晋霜[1] 张明峰 Fu Lili;Guo Qiang;Yu Guo(Department of Endocrinology and Metabolism,Chengdu First People′s Hospital,Chengdu,Sichuan 610041,China)

机构地区：[1]成都市第一人民医院内分泌代谢科,四川成都610041

出　　处：《四川医学》2020年第7期696-700,共5页Sichuan Medical Journal

摘　　要：目的探究非低血糖状态下饥饿感与2型糖尿病(T2DM)患者低血糖恐惧、睡眠质量、生活质量关系以及高纤低糖食物对患者干预效果。方法选取2019年5至11月150例饥饿感视觉模拟评分(VAS)≥1分的T2DM患者为研究对象,另选50例VAS评分为0分的T2DM患者进行对照,比较饥饿组与非饥饿组入院时低血糖恐惧量表(FH-15)、匹兹堡睡眠质量指数(PSQI)及糖尿病患者生存质量量表(DSQL)得分,并分析饥饿组VAS评分与FH-15、PSQI及DSQL得分相关性;饥饿组根据是否进食高纤低糖食物分为观察组73例、对照组77例,观察组在原饮食结构基础上,每日补充2次新鲜黄瓜或西红柿,每次100 g,对照组维持原饮食结构不变,连续干预1个月,比较两组干预前、后夜间(22:00)血糖值、每日饥饿VAS评分>3分次数、夜间饥饿VAS评分、FH-15、PSQI、DSQL得分。结果饥饿组入院时FH-15、PSQI、DSQL得分均显著高于非饥饿组(P<0.05),饥饿组饥饿VAS评分与FH-15、PSQI、DSQL得分均呈正相关(P<0.05),且FH-15、PSQI、DSQL得分互呈正相关(P<0.05);干预后,两组夜间血糖值比较差异无统计学意义(P>0.05),但观察组每日饥饿VAS评分>3分次数、夜间VAS评分、FH-15、PSQI、DSQL得分均显著低于对照组(P<0.05)。结论T2DM非低血糖状态下饥饿感可增加患者低血糖恐惧、影响其睡眠质量及生存质量,给予高纤维低糖食物干预有利于改善患者饥饿感、降低其低血糖恐惧,同时提高患者睡眠质量及生活质量,且不升高夜间血糖。Objective To explore the relationship between hunger sensation and hypoglycemia,sleep and life quality of type 2 diabetes(T2DM)patients under non-hypoglycemia state,and the effect of high-fiber and low-sugar food intervention on patients.Methods From May 2019 to November 2019,150 T2DM patients with visual analogue score(VAS)≥1 were selected as the research subjects.Another 50 T2DM patients with 0 VAS score were selected as controls.The scores of fear hypoglycemia scale(FH-15),Pittsburgh sleep quality index(PSQI)and diabetes specific quality of life(DSQL)in the hungry and non-hungry group were compared.The correlation between VAS score and FH-15,PSQI and DSQL scores in hungry group were analyzed.Meanwhile,hungry group was divided into observation group(OG,n=73)and control group(CG,n=77)according to whether they ate high-fiber and low-sugar food or not.On the basis of original diet structure,fresh cucumber or tomato(twice a day,100g each time)were offered to OG for 1 month,while CG remained the original diet structure.The blood glucose levels at night(22:00),times of daily hunger VAS score>3,score of night hunger VAS,FH-15,PSQI and DSQL were compared between two groups before and after intervention.Results The scores of FH-15,PSQI and DSQL in hungry group were significantly higher than those of non-starved group(P<0.05).The hungry VAS score was positively correlated with the FH-15,PSQI and DSQL scores(P<0.05),and FH-15,PSQI and DSQL scores were positively correlated with each other(P<0.05).There was no significant difference in night blood glucose levels after intervention(P>0.05),but times of OG’s daily hunger VAS score>3,night VAS score,FH-15,PSQI and DSQL scores were significantly lower than those of CG(P<0.05).Conclusion Hunger of T2DM under non-hypoglycemic state could increase patient s hypoglycemia fear to affect their sleep and life quality.Intervention with high-fiber and low-sugar foods could be helpful to improve patient s hunger,reduce their fear of hypoglycemia and improve patient s sleep and life

关 键 词：二型糖尿病 饥饿感 非低血糖状态 睡眠质量 生活质量 高纤低糖食物 

分 类 号：R587.1[医药卫生—内分泌]