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作 者:王亚楠 马艳芳[2] 陈艳妮 郭亚雄[2] 李才垚 张也 耿亮亮 刘乾生[2] 金瑄[2] WANG Yanan;MA Yanfang;CHEN Yanni;GUO Yaxiong;LI Caiyao;ZHANG Ye;GENG Liangliang;LIU Qiansheng;JIN Xuan(Shaanxi University of Chinese Medicine,Xianyang 712046,China;The First Clinical Medical College of Shaanxi University of Chinese Medicine,Xianyang 712000,China;Xi′an Children′s Hospital,Xi′an 710000,China;Xi′an Jiaotong University,Xi′an 710000,China)
机构地区:[1]陕西中医药大学,咸阳712046 [2]陕西中医药大学第一临床医学院,咸阳712000 [3]西安儿童医院,西安710000 [4]西安交通大学,西安710000
出 处:《世界中医药》2020年第16期2486-2489,共4页World Chinese Medicine
基 金:国家自然科学基金项目(61503295)——孤独症儿童脑缺省网络构建及其与心智理论能力缺失的关联研究;陕西省儿科医联体课题(2018B02)——早产儿运动落后干预模式的有效性的临床研究对照;西安市卫计委课题Ⅱ类(J201902033)——唾液酸梅与转移酶在孤独症谱系障碍儿童与正常儿童基因差异研究;陕西中医药大学中西医结合防治脑发育障碍性疾病创新团队项目(陕中大学科办[2018]1号)。
摘 要:孤独症(自闭症)是一种发生于儿童早期的发育障碍性疾病。目前西医对本病病因的认识仍不明确,但提出了很多假说,近年来以肠道菌群为病因的说法更为流行,认为与脑-肠轴的关系紧密,且无特效的治疗药物。中医历史古籍没有对“孤独症”病名的明确记载,但并不缺乏对本病病因病机及核心症状的阐述。本文重点从脾肾-脑相通理论和肠道菌群的相关性着手,探究中医治疗孤独症的思路。Autism is a developmental disorder that occurs in early childhood.At present,Western medicine′s understanding of the cause of this disease is still unclear,but many hypotheses have been put forward.In recent years,the theory of intestinal flora as the cause has become more popular.It is believed that it is closely related to the brain-gut axis and has no specific therapeutic drugs.There is no clear record of the name of“Autism”in ancient Chinese medicine history books,but there is no lack of explanations of the etiology,pathogenesis and core symptoms of the disease.The paper focuses on the spleen-kidney-brain communication theory and the correlation with the intestinal flora,in order to explores the thinking of TCM treatment for Autism.
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