孕前体检夫妇乙型肝炎五项检测结果分析  

Analysis of The Results of Five Tests of Hepatitis B in Pre-pregnancy Physical Examination

作　　者：郑金燕 ZHENG Jinyan(Department of Clinical Laboratory, Zhengzhou Jinshui District Maternal and Child Health Care Center, Zhengzhou Henan 450000, China)

机构地区：[1]郑州市金水区妇幼保健所检验科,郑州450000

出　　处：《河南医学高等专科学校学报》2020年第4期428-431,共4页Journal of Henan Medical College

摘　　要：目的探讨孕前体检夫妇乙型肝炎(乙肝)五项检测结果。方法选取进行孕前乙肝五项检查的2432对夫妇(4864人),头胎备孕夫妇2100对(4200人),二胎备孕夫妇332对(664人)。抽取所有参与本次检查夫妇的清晨空腹肘静脉血,采用酶联免疫吸附法检测乙肝五项。比较城镇及农村、不同年龄及学历备孕夫妇乙型肝炎病毒(HBV)感染情况;头胎与二胎备孕夫妇乙肝五项检测结果,包括乙肝表面抗原(HBsAg)、乙肝表面抗体(HBsAb)、e抗原(HBeAg)、e抗体(HBeAb)及核心抗体(HBcAb)。结果年龄20~29岁的高中及以下学历的农村孕前检查者HBV感染率较高,差异有统计学意义(P<0.05);头胎备孕夫妇中男性乙肝大三阳及小三阳检出率为15.38%,HBV感染率为42.38%,女性乙肝大三阳及小三阳检出率为14.19%,HBV感染率为41.05%;二胎备孕夫妇中男性乙肝大三阳及小三阳阳性检出率为15.06%,HBV感染率为51.81%,女性乙肝大三阳及小三阳阳性检出率为11.75%,HBV感染率为50.00%。头胎及二胎备孕夫妇乙肝大小三阳及HBV检出率比较,差异无统计学意义(P>0.05)。结论对备孕夫妇给予孕前乙肝五项检测有助于及时发现HBV感染现象,以便根据检测结果制定相应的治疗干预措施,可有效控制乙肝发病率,提高新生儿健康水平。Objective To explore the results of five tests of hepatitis B in pre-pregnancy physical examination couples.Methods 2432 couples who underwent five pre-pregnancy Hepatitis B tests in our institute were selected.There were 2100 couples with preparation for the first pregnancy(4200 people),and 332 couples with preparation for the second pregnancy(664 people).All the couples who participated in this examination were taking the fasting elbow venous blood,and the five items of Hepatitis B were detected by ELISA.Compared HBV infection among couples with preparation for pregnancy of different ages and education levels in urban and rural.The results of five Hepatitis B tests of couples with preparation for the first and second pregnancy were analyzed,including Hepatitis B surface antigen(HBsAg),Hepatitis B surface antibody(HBsAb),e antigen(HBeAg),e antibody(HBeAb)and core antibody(HBcAb).Results The prevalence of HBV infection in rural pre-pregnancy examiners aged 20-29 years old with high school education and below is higher,the difference is statistically significant(P<0.05);Among the couples with first pregnancy preparation,the detection rate of male HBsAg,HBeAg,HBcAb positive and HBsAg,HBeAb,HBcAb positive was 15.38%,hepatitis B virus infection rate was 42.38%,female HBsAg,HBeAg,HBcAb positive and HBsAg,HBeAb,HBcAb positive detection rate was 14.19%,and Hepatitis B virus infection rate was 41.05%,respectively.Among the couples with second pregnancy preparation,the detection rate of male HBsAg,HBeAg,HBcAb positive and HBsAg,HBeAb,HBcAb positive was 15.06%,the infection rate of Hepatitis B virus was 51.81%,the detection rate of female HBsAg,HBeAg,HBcAb positive and HBsAg,HBeAb,HBcAb positive was 11.75%,hepatitis B virus infection rate was 50.00%,respectively.There was no statistically significant difference in the detection rates of HBsAg,HBeAg,HBcAb positive and HBsAg,HBeAb,HBcAb positive and hepatitis B virus infection rate between couples with preparation for the first and second pregnancy(P>0.05).Conclusion Five te

关 键 词：乙肝五项检测 孕前体检 乙型肝炎病毒 大三阳 小三阳 

分 类 号：R512.62[医药卫生—内科学]