妇女既往孕次及产次对新生儿出生体重影响的队列研究  

Cohort study on the relationship between women’s previous gravidity,parity and birth weight of neonates

作　　者：庾静云 曾思良[1] 刘建新[1] 姜碧 YU Jing-yun;ZENG Si-liang;LIU Jian-xin;JIANG Bi(Dongguan Maternal and Child Health Hospital of Guangdong Province,Dongguan,Guangdong 523000,China)

机构地区：[1]东莞市妇幼保健院,广东东莞523000

出　　处：《现代预防医学》2020年第16期2963-2966,共4页Modern Preventive Medicine

基　　金：国家科技基础性工作专项重点项目(2013FY110500);东莞市社会科技发展项目(201950715007842)。

摘　　要：目的探讨妇女既往孕次及产次对新生儿出生体重的影响。方法基于东莞市免费婚前健康检查和孕前优生健康检查项目,获取受检对象检查结果,追踪随访获取其妊娠结局情况。采用无序多分类logistic回归探讨妇女既往孕次及产次与小于胎龄儿(SGA)、大于胎龄儿(LGA)、低体重出生儿(LBWI)及巨大儿发生率的关系。结果共有17 783名对象参与;调整相关混杂因素后,妇女既往孕次>1次是分娩LGA(RR=1.59,95%CI:1.36~1.85)和巨大儿(RR=1.87,95%CI:1.49~2.35)的危险因素,但可降低分娩SGA(RR=0.70,95%CI:0.60~0.81)和LBWI (RR=0.73,95%CI:0.60~0.89)的风险;妇女既往产次>1次增加分娩LGA(RR=1.74,95%CI:1.40~2.17)和巨大儿(RR=1.98,95%CI:1.45~2.71)的风险,但可降低分娩SGA(RR=0.70,95%CI:0.54~0.90)和LBWI(RR=0.63,95%CI:0.44~0.91)的风险。结论妇女既往孕次、产次对新生儿出生体重有影响,应做好产前保健和健康教育工作。Objective To investigate the effect of women’s previous gravidity,parity on birth weight of neonates.Methods Based on the free pre-marital health check-ups and pre-pregnancy eugenic health check-ups in Dongguan,the examination results of the subjects were obtained,and the pregnancy outcomes were followed up.Multinomial logistic regression models were used to analyze the relationship between women’s previous gravidity,parity and small for gestational age(SGA),large for gestational age(LGA),low birth weight infant(LBWI)and macrosomia.Results A total of 17783 subjects were included in the analysis.After adjusting for related confounders,previous gravidity>1 times appeared as a risk factor for LGA(RR=1.59,95%CI:1.36-1.85)and macrosomia(RR=1.87,95%CI:1.49-2.35),and was also associated with the decreased risk of SGA(RR=0.70,95%CI:0.60-0.81)and LBWI(RR=0.73,95%CI:0.60-0.89).And previous parity>1 times increased the risk of LGA(RR=1.74,95%CI:1.40-2.17)and macrosomia(RR=1.98,95%CI:1.45-2.71),while would decreased risk of SGA(RR=0.70,95%CI:0.54-0.90)and LBWI(RR=0.63,95%CI:0.44-0.91).Conclusion Women’s previous gravidity,parity had an impact on birth weight of neonates,which should be highlighted in prenatal care and health education well.

关 键 词：孕次 产次 出生体重 队列研究 

分 类 号：R173[医药卫生—妇幼卫生保健]