原发性干燥综合征的流行病学研究进展  

Advances in the epidemiology of primary Sjogren’s syndrome

作　　者：张欢[1,2] 刘春红 吴斌 ZHANG Huan;LIU Chun-hong;WU Bin(Hunan University of Traditional Chinese Medicine,Changsha,Hunan 410208,China;不详)

机构地区：[1]湖南中医药大学,湖南长沙410208 [2]重庆市中医院风湿病科,重庆400021

出　　处：《现代预防医学》2020年第16期3056-3058,3063,共4页Modern Preventive Medicine

基　　金：重庆市科委项目(cstc2018jxjl130084,cstc2019jscx-dxwtBX0023);重庆市卫健委重点项目(ZY201801009)。

摘　　要：目的分析原发性干燥综合征的流行病特征,为干燥综合征的防控措施提供依据。方法检索知网、万方、维普、pubmed等数据库,查找关于原发性干燥综合征的流行病学研究,对其整理总结和分析。结果原发性干燥综合征发病率和患病率在世界各地差异较大,年龄、性别、种族、地理位置、职业暴露等是其危险因素,疾病活动和感染是患者住院的主要原因;原发性干燥综合征的并发症较多,心血管和神经系统受累、恶性肿瘤和感染等导致死亡率升高。现分类标准尚不统一,在一定程度上影响了流行病调查的可比性。结论原发性干燥综合征的危险因素和并发症较多,应积极防治并发症以降低死亡率。Objective The aim of this study was to analyze of the epidemiological characteristics of primary Sjogren’s ssyndrome,in order to provide basis for targeted prevention and treatment measures.Methods Databases including CNKI,VIP,WanFang and pubmed were searched to find epidemiological stud ies o n primary Sjogren’s syndrome,and the studies were summarized and analyzed.Results The incidence and prevalence of primary Sjogren’s syndrome varied widely around the world,with age,gender,race,geographic location,occupational exposure,etc.as risk factors.Major causes of hospitalization were disease activity and infection.Primary Sjo?gren’s syndrome had many complications,including cardiovascular and nervous system involvement,malignant tumors and infections,leading to increased mortality.The comparability of epidemiological investigation was affected by the inconsistency of diagnostic criteria.Conclusion There were many risk factors and complications of primary Sjogren’s syndrome,and complications should be actively controlled to reduce mortality.

关 键 词：干燥综合征 流行病学 综述 

分 类 号：R593[医药卫生—内科学]