右美托咪定对阻塞性睡眠呼吸暂停综合征患者腭咽成型术后睡眠功能的影响研究  

Effect of Dexmedetomidine on Sleep Function in Patients with Obstructive Sleep Apnea Syndrome after Velopharyngeal Angioplasty

作　　者：胡惠蓉[1,2] 陈彬琼 HU Huirong;CHEN Binqiong(Department of Anesthesiology,the Second Affiliated Hospital of Fujian Medical University,Quanzhou 362000,China;Ultrasound department of the Second Affiliated Hospital of Fujian Medical University,Quanzhou 362000,China)

机构地区：[1]福建医科大学附属第二医院麻醉科,泉州362000 [2]福建医科大学附属第二医院超声科,泉州362000

出　　处：《世界睡眠医学杂志》2020年第7期1273-1274,共2页World Journal of Sleep Medicine

摘　　要：目的:探讨右美托咪定对阻塞性睡眠呼吸暂停综合征患者腭咽成型术后睡眠功能的影响。方法:选取2018年8月至2019年8月福建医科大学附属第二医院收治的行腭咽成型术治疗的重度阻塞性睡眠呼吸暂停综合征患者64例作为研究对象,分为观察组和对照组,每组32例。观察组采用右美托咪定输注治疗,对照组采用常规麻醉治疗。比较2组患者术后睡眠功能。结果:2组患者快动眼睡眠比例、3-4期睡眠比例、最低血氧饱和度、呼吸暂停低通气指数比较,差异有统计学意义(P<0.05)。结论:重度阻塞性睡眠呼吸暂停综合征患者在腭咽成型术中进行右美托咪定持续输注,能显著改善患者的术后睡眠功能,值得应用。Objective:To investigate the effect of dexmedetomidine on sleep function in patients with obstructive sleep apnea syndrome after velopharyngeal plastic surgery.Methods:A total of 64 patients with severe obstructive sleep apnea syndrome who underwent pharyngoplasty in The Second Affiliated Hospital of Fujian Medical Universityfrom August 20 to August 2019 were enrolled in the observation group(n=32,dexmedetomidine infusion).The postoperative sleep function of the two groups was compared with the control group(n=32,routine anesthesia).Results:There were significant differences in the ratio of rapid eye movement sleep,3-4 stage sleep,minimum oxygen saturation,and apnea hypopnea index between the two groups(P<0.05).Conclusion:Continuous dexmedetomidine infusion in patients with severe obstructive sleep apnea syndrome can significantly improve postoperative sleep function and is worthy of application.

关 键 词：腭咽成型术 右美托咪定 睡眠功能 阻塞性睡眠呼吸暂停综合征 

分 类 号：R659[医药卫生—外科学] R614[医药卫生—临床医学]