壳聚糖通过减少自由基堆积提高对运动训练小鼠抗疲劳能力的实验研究  

Experimental Study of Chitosan Improving the Anti-fatigue Ability of Sports Training Mice by Reducing the Accumulation of Free Radicals

作　　者：王耀东[1] 邱丽 孙梦佳 WANG Yaodong;QIU Li;SUN Mengjia(Dept.of PE,China University of Mining and Technology-Beijing,Beijing 100083,China;Department of Basic Styudies,Shangdong Xian-dai University,Jinan 250104,China)

机构地区：[1]中国矿业大学(北京)体育教研部,北京100083 [2]山东现代学院基础部,山东济南250104

出　　处：《天津体育学院学报》2020年第4期434-438,共5页Journal of Tianjin University of Sport

基　　金：中央高校基本科研业务费专项资金资助项目(项目编号:2009QS10)。

摘　　要：目的:探究游泳运动联合壳聚糖对延缓小鼠疲劳及促进恢复的可能机制。方法:对KM小鼠分别进行壳聚糖(低、中、高剂量)干预、游泳运动干预、壳聚糖、(低、中、高剂量)和游泳运动联合干预,检测干预后大鼠力竭时间、HB、LD、SOD、MDA和肌/肝糖原等指标。结果:游泳运动与壳聚糖联合干预组小鼠到达力竭时间均显著高于对照组,其中联合干预较游泳运动可显著上调小鼠HB,降低LD和MDA浓度,提升SOD活力和肌/肝糖原含量。结论:游泳运动联合壳聚糖干预可通过改善自由基的代谢速度,降低自由基对身体脏器及细胞的氧化损伤,有效延缓疲劳的出现,促进疲劳后恢复。Objective:To explore the possible mechanism of swimming combined with chitosan on delaying fatigue and promoting recovery in mice.Methods:KM mice were treated with chitosan(low,medium and high dose)intervention,swimming exercise intervention,chitosan(low,medium and high dose)and swimming combined intervention.The time of exhaustion,HB,LD,SOD,MDA and muscle/liver glycogen were measured after intervention.Results:the exhaustion time of mice in swimming and chitosan combined intervention group was significantly higher than that in the control group.Compared with swimming,the combined intervention could significantly increase HB,reduce LD and MDA concentration,enhance SOD activity and muscle/liver glycogen content.Conclusions:Swimming combined with chitosan intervention can improve the metabolic rate of free radicals,reduce the oxidative damage of free radicals to organs and cells,effectively delay the occurrence of fatigue and promote recovery after fatigue.

关 键 词：壳聚糖 游泳运动 小鼠 超氧化歧化酶 血乳酸 HB 

分 类 号：G804.2[文化科学—运动人体科学]