慢型克山病患者生存质量评估及影响因素分析  

Assessment of quality of life in patients with chronic Keshan disease and analysis of its influencing factors

作　　者：李萍[1] 孙璐璐 鱼素琴[1] 何健[1] 康建业 王平 邵建赟[1] 陈晓燕[1] 王燕玲[1] 王芸[5] 苏莉[2] Li Ping;Sun Lulu;Yu SuQin;He Jian;Kang Jianye;Wang Ping;Shao Jianyun;Chen Xiaoyan;Wang Yanling;Wang Yun;Su Li(Department for Endemic Disease Prevention and Control,Gansu Center for Disease Prevention and Control,Lanzhou 730000,China;Department of Child and Adolecent Health,School of Public Health,Lanzhou University,Lanzhou 730000,China;Jingchuan Center for Disease Prevention and Control,Pingliang 744300,China;Department of Cardiology,Jingchuan People's Hospital,Pingliang 744300,China;Department for Endemic Disease Prevention and Control,Qingyang Center for Disease Prevention and Control,Qingyang 745000,China)

机构地区：[1]甘肃省疾病预防控制中心地方病控制科,兰州730000 [2]兰州大学公共卫生学院儿少卫生与妇幼保健研究所,730000 [3]甘肃省泾川县疾病预防控制中心,平凉744300 [4]甘肃省泾川县人民医院心内科,平凉744300 [5]甘肃省庆阳市疾病预防控制中心地方病所,745000

出　　处：《中华地方病学杂志》2020年第8期557-561,共5页Chinese Journal of Endemiology

基　　金：甘肃省科技厅自然科学基金项目 (18JR3RA042);甘肃省中医药管理局科研项目 (GZK-2013-47);庆阳市科技支撑项目 (KZ2015-54)。

摘　　要：目的评估慢型克山病患者的生存质量,并探讨与之相关的影响因素,以期为提高慢型克山病患者的生存质量提供理论依据。方法依据《克山病诊断》(WS/T 210-2011)标准,选择甘肃省平凉市泾川县人民医院规范治疗的110例慢型克山病患者为研究对象,采用问卷调查收集患者人口学资料、病情资料,明尼苏达心力衰竭量表(Minnesota living with heart failure questionnaire,MLHFQ)评估患者生存质量;并应用相关分析对患者MLHFQ评分的影响因素进行分析。结果在110例慢型克山病患者中,男性66例、女性44例,年龄为(60.93±8.22)岁;文化程度以初中及以下学历为主,占92.73%(102/110);平均家庭年收入为2.07万元;患者心胸比为0.64±0.09;射血分数(EF)为(36.71±7.55)%;劳动能力分级以简单活动为主,占60.91%(67/110);心功能分级主要为Ⅲ级,占67.27%(74/110)。慢型克山病患者MLHFQ总分为(69.17±16.14)分,身体、情绪及其他领域评分分别为(26.32±6.70)、(15.86±4.96)、(26.94±6.10)分。不同文化程度、心胸比、EF、劳动能力分级、心功能分级、家庭年收入的患者,MLHFQ总分比较差异有统计学意义(F=7.121、6.236、4.515、3.427、5.418,Z=2.346,P均<0.05)。相关分析结果显示,文化程度、劳动能力分级与身体领域和其他领域评分呈负相关(r=-0.302、-0.206,-0.343、-0.285,P均<0.01),家庭年收入与情绪领域评分呈负相关(r=-0.263,P<0.01);心功能分级与身体领域和其他领域评分呈正相关(r=0.233、0.210,P均<0.05)。结论慢型克山病患者生存质量较差,患者的文化程度、家庭年收入、劳动能力分级、心功能分级等均会影响其生存质量。Objective To evaluate the quality of life of patients with chronic Keshan disease,and to explore related influencing factors,in order to provide a theoretical basis for improving the quality of life of patients with chronic Keshan disease.Methods According to the standard of"Diagnosis of Keshan Disease"(WS/T 210-2011),110 patients with chronic Keshan disease treated in the Jingchuan People's Hospital,Pingliang City,Gansu Province were selected as the research subjects,and demographic and disease data of the patients were collected by questionnaire survey;the quality of life of patients was assessed by the Minnesota living with heart failure questionnaire(MLHFQ);and correlation analysis was used to analyze and explore the influencing factors of patients'MLHFQ score.Results Among the 110 patients with chronic Keshan disease,66 were males and 44 were females,aged(60.93±8.22)years;the education level was mainly junior high school or below,accounting for 92.73%(102/110);average annual family income was 20700 yuan;the cardio-thoracic ratio of the patient was 0.64±0.09;the ejection fraction(EF)was(36.71±7.55)%;the labor ability classification was mainly based on simple activities,accounting for 60.91%(67/110);and the cardiac function classification was mainly GradeⅢ,accounting for 67.27%(74/110).The total MLHFQ scores of chronic Keshan patients were(69.17±16.14)points,and the scores of physical,emotional and other fields were(26.32±6.70),(15.86±4.96)and(26.94±6.10)points,respectively.The total MLHFQ scores had statistically significant differences among patients with different education level,cardio-thoracic ratio,EF,labor ability classification,cardiac function classification and annual family income(F=7.121,6.236,4.515,3.427,5.418,Z=2.346,P<0.05).The results of correlation analysis showed that educational level and labor ability classification were negatively correlated with scores in physical field and other fields(r=-0.302,-0.206,-0.343,-0.285,P<0.01),and annual family income was negatively correlated with

关 键 词：克山病 生存质量 明尼苏达心力衰竭量表 影响因素 

分 类 号：R542.3[医药卫生—心血管疾病]