薄层色谱法快速检查复方罗布麻片Ⅰ中掺伪大花罗布麻叶方法研究  

Study on the Adulteration Detection of Poacynum Hendersonni(Hook.f)Wodson in Compound Luobuma Tablets Ⅰ by TLC

作　　者：谢思敏[1] 侯惠婵[1] 顾利红[1] XIE Simin;HOU Huichan;GU Lihong(Guangzhou Institute for Drug Control,Guangzhou,Guangdong 510160,China)

机构地区：[1]广州市药品检验所,广东广州510160

出　　处：《今日药学》2020年第8期538-540,共3页Pharmacy Today

基　　金：国家药典委员会项目(2018X001)。

摘　　要：目的建立薄层色谱法快速检查复方罗布麻片Ⅰ中罗布麻叶在生产过程中是否存在掺伪大花罗布麻叶的方法。方法以硅胶G为薄层板,以白麻苷为对照品,建立薄层色谱检查方法。结果薄层色谱斑点清晰,罗布麻片Ⅰ中罗布麻叶阴性对照无干扰。结论建立的方法操作简单、快捷,能有效的检查复方罗布麻片Ⅰ中罗布麻叶是否存在掺伪大花罗布麻叶的情况,同时为进一步修订和完善复方罗布麻片Ⅰ标准提供试验依据。OBJECTIVE TLC are used to explore whether there is adulteration of Apocynum venetum L.in compound Luobuma tablets Ⅰ in the production process.METHODS The TLC method was established by using Quercetin-3-O-sophoroside as reference on silica G thin layer plate.RESULTS The TLC spots were clear,and negative control had no interference.CONCLUSION The established method is simple and fast,which can effectively adulterate the Apocynum venetum L.in compound Luobuma tablets Ⅰ.

关 键 词：复方罗布麻片Ⅰ 罗布麻叶 大花罗布麻叶 薄层色谱 

分 类 号：R917[医药卫生—药物分析学]