初筛核酸阴性的新型冠状病毒肺炎1例  

A COVID-19 patient with negative viral nucleic acid in primary screening

作　　者：王岩[1] 刘洪艳[1,3] 吴彤[1] 田霞[1,4] 吕东霞[2] 宋晓丹[1,5] 吕呈 谷野[1] WANG Yan;LIU Hong-yan;WU Tong;TIAN Xia;LÜ Dong-xia;SONG Xiao-dan;LÜ Cheng;GU Ye(COVID-19 Group,the Sixth People’s Hospital of Shenyang,110006,China)

机构地区：[1]沈阳市第六人民医院COVID-19小组,110006 [2]沈阳市第六人民医院消化门诊,110006 [3]沈阳市第六人民医院感染一科,110006 [4]沈阳市第六人民医院中医康复门诊,110006 [5]沈阳市第六人民医院发热门诊,110006

出　　处：《传染病信息》2020年第4期362-365,共4页Infectious Disease Information

基　　金：沈阳市防治新型冠状病毒感染肺炎科研攻关应急专项(YZ2020-9-009)。

摘　　要：理论上核酸检测是能最早确诊新型冠状病毒感染的方法,但临床核酸检测结果存在假阴性的情况。本例病例提示,对于COVID-19疑似患者,病毒核酸检测1次甚至2次阴性,不能简单排除,应密切追踪患者流行病学史及影像学改变,动态检测核酸,以免漏诊,错过早期治疗时机,造成疾病传播。流行病学史、影像学及采样时机、标准等对疾病诊断和病变程度判断具有重要意义。Detection of nucleic acid is a method to first confirm COVID-19 theoretically,but it may show false negative result in clinical practice.This study indicates that suspected patients with COVID-19 cannot be ruled out easily because of once or twice negative results of nucleic acid detection.The epidemiology and radiological findings should be closely monitored.Dynamic test for viral nucleic acid is needed to avoid missed diagnosis,thus causing the spread of disease and missing the best time for early treatment.Clinical epidemiology,radiological findings,sampling time and criteria have posed significance to diagnose the disease and judge the severity.

关 键 词：新型冠状病毒 新型冠状病毒肺炎 病毒核酸检测 

分 类 号：R563[医药卫生—呼吸系统]