儿童原发性免疫缺陷病呼吸系统并发症研究进展  

Study progress of respiratory complications of primary immunodeficiencies in children

作　　者：樊慧峰[1] 陈晨[1] 卢根[1] Fan Huifeng;Chen Chen;Lu Gen(Department of Respiratory,Guangzhou Women and Children′s Medical Center,Guangzhou Medical University,Guangzhou 510120,China)

机构地区：[1]广州医科大学附属广州市妇女儿童医疗中心呼吸科,510120

出　　处：《中华实用儿科临床杂志》2020年第16期1274-1277,共4页Chinese Journal of Applied Clinical Pediatrics

摘　　要：原发性免疫缺陷病(PIDs)是由免疫系统一种或多种缺陷造成的一组疾病。PIDs患儿常因发生多次严重的感染而形成一系列并发症,其中呼吸系统疾病为临床最常见的首发症状。肺部并发症在PIDs患儿中具有较高的发病率和病死率,而各类的PIDs有其不同的致病病原谱。早期诊断和合理治疗可以预防或减缓PIDs呼吸系统并发症的病程。现就常见的PIDs在儿童呼吸系统的表现进行综述。Primary immunodeficiencies(PIDs)are caused by one or more defects of the immune system.Children with PIDs are more likely to experience recurrent and/or severe infections and tend to develop a wide range of complications.Respiratory diseases are the main and initial manifestation in most cases.Pulmonary complications have significant morbidity and mortality in children with PIDs.The spectrum of pathogens usually varies among different types of PID.Early diagnosis and appropriate therapy can prevent or at least slow down the development and course of respiratory complications of PIDs.In this study,the main respiratory manifestations of common PIDs in children are reviewed.

关 键 词：原发性免疫缺陷病 呼吸系统并发症 儿童 

分 类 号：R725.6[医药卫生—儿科]