α-羰酰氧基苯乙酮及α-羟基苯乙酮的制备  

Preparation ofα-Carbonyloxy-acetophenone and α-Hydroxyacetophenone

作　　者：陈小文 黄志诚 邹滢 李霞 宋祥家 任红霞 田芳[1] 王立新[1] CHEN Xiao-wen;HUANG Zhi-cheng;ZOU Ying;LI Xia;SONG Xiang-jia;REN Hong-xia;TIAN Fang;WANG Li-xin(Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China;University of Chinese Academy of Sciences, Beijing 100049, China)

机构地区：[1]中国科学院成都有机化学研究所,四川成都610041 [2]中国科学院大学,北京100049

出　　处：《合成化学》2020年第8期732-735,共4页Chinese Journal of Synthetic Chemistry

摘　　要：以季铵盐为催化剂,由α-溴代苯乙酮合成α-羰酰氧基苯乙酮,然后在碱性条件下,高效制备了α-羟基苯乙酮,转化率和选择性分别为100.0%和91.2%,其结构经1H NMR确证。A novel and efficient preparation route ofα-carbonyloxy-acetophenone fromα-bromoacetophenone in the presence of quaternary ammonium salt was described.α-Hydroxy-acetophenone was effectively(100%conversation and 91.2%selectivity)prepared after basic hydrolysis ofα-carbonyl acetophenone and carboxylate may be reused.The structure was confirmed by 1H NMR.

关 键 词：α-溴代苯乙酮 α-羰酰氧基苯乙酮 α-羟基苯乙酮 制备 工艺优化 

分 类 号：O62[理学—有机化学]