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作 者:马妮娜[1] 路平[1] 王露朝 罗超 MA Nina;LU Ping;WANG Luchao(Department of Cardiology,Hanzhong Central Hospital,Shaanxi Province,Hanzhong 723000)
机构地区:[1]陕西省汉中市中心医院心内科,汉中723000
出 处:《陕西医学杂志》2020年第9期1098-1101,共4页Shaanxi Medical Journal
基 金:陕西省科技厅重点研发项目(2017-SF-073)。
摘 要:目的:探究长期透析时间下尿毒症患者左心室功能的变化及组织多普勒成像(TDI)Tei指数对其的评估价值。方法:选取长期(≥1年)尿毒症患者56例作为尿毒症组,另选择同期体检健康者50例作为对照组,两组均行常规二维超声及TDI检查,测量Tei指数并进行对比分析。结果:尿毒症组左房内径(LAD)、左室舒张末期内径(LVDd)、室间隔厚度(IVSd)、左室后壁厚度(LVPWd)及收缩末期左室内径(LVDs)、室间隔厚度(IVSs)、左室后壁厚度(LVPWs)较对照组均有显著增大(P<0.05)。尿毒症组左心室射血分数(EF)和短轴缩短率(FS)与对照组比较,差异无统计学意义(P>0.05)。尿毒症组二尖瓣口舒张早期血流峰值流速(E)、舒张晚期血流峰值流速(A)较对照组均有显著增大(P<0.05),但E/A值比较差异无统计学意义(P>0.05)。尿毒症组左室等容舒张时间(IRT)、等容收缩时间(ICT)及Tei指数较对照组均有显著增大(P<0.05),但射血时间(ET)显著降低(P<0.05)。结论:≥1年透析时间的尿毒症患者的左心室室腔显著增大,左心室明显肥厚,心脏舒张功能和收缩功能均已受损。TDI-Tei指数可作为整体评价左心室功能变化的有效指标。Objective:To investigate the changes of left ventricular function in uremia patients undergoing long-term dialysis and the evaluation value of tissue Doppler(TDI)Tei index.Methods:56 uremia patients underwent long-term(longer than 1 year)dialysis were selected as the uremia group.50 healthy subjects who received physical examination during the same period were selected as the control group.Two dimensional ultrasound and TDI were performed in both groups.Tei index was measured and compared.The Tei index was measured and comparatively analyzed.Results:LAD,LVDd,IVSd,LVPWd,LVDs,IVSs and LVPWs in uremia group were significantly larger than those in control group(P<0.05).There was no statistical difference in left ventricular ejection fraction(EF)and shortening fraction(FS)between the two groups(P>0.05).The peak flow velocity in early diastolic flow velocity(E)and the peak flow velocity in late diastolic period(A)in uremia group were higher than those in control group(P<0.05),but there was no statistical difference in E/A between the two groups(P>0.05).The isovolumic relaxation time(IRT),isovolumic contraction time(ICT),and Tei index of the left ventricular in uremia group were longer/larger than those in control group,while the ejection time(ET)was shorter than that in control group(P<0.05).Conclusion:In uremic patients with dialysis time≥1 year,the left ventricular cavity is significantly enlarged,the left ventricle is significantly thickened,and the diastolic and systolic functions of the heart are damaged.TDI Tei index can be used as an effective index to evaluate the changes of left ventricular function.
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