李铁教授辨证治疗乳腺癌术后激素受体阳性高危患者临床观察  

Clinical Observation on Professor Li Tie in the Treatment of High Risk Patients with Hormone Receptor Positive after Breast Cancer Surgery Based on Syndrome Differentiation

作　　者：汪莉[1] 李铁[1] 杜红旭[1] 周正国[1] WANG Li;LI Tie;DU Hongxu;ZHOU Zhengguo(Oncology Department,Dalian Second People’s Hospital(Dalian Hospital of Integrated Traditional Chinese and Western Medicine),Liaoning Province,Dalian 116011,China)

机构地区：[1]大连市第二人民医院(大连市中西医结合医院)肿瘤科,辽宁大连116011

出　　处：《中国中医药现代远程教育》2020年第15期63-65,共3页Chinese Medicine Modern Distance Education of China

摘　　要：目的探讨中医辨证治疗乳腺癌术后激素受体阳性高危患者的临床效果。方法选取2016年2月—2019年2月李铁全国名老中医药专家传承工作室医治的60例乳腺癌术后激素受体阳性高危患者作为研究对象,随机将60例患者分为观察组(n=30)和对照组(n=30),对照组患者行内分泌治疗,观察组患者行中医辨证治疗,比较2组患者的治疗效果。结果观察组一年无病生存率为90.00%(27/30)显著高于对照组的80.00%(24/30),统计学差异显著(х2=3.9216,P=0.0476)。2组生存质量对比,其中生理职能、躯体疼痛的评分统计学差异显著(P<0.05),社会功能、生理功能、情感智能、活动能力及精神健康的评分差异无统计学差异(P>0.05)。观察组不良反应发生率为6.67%低于对照组的16.67%,有统计学差异(х2=4.8505,P=0.0276)。结论在乳腺癌术后激素受体阳性高危患者的治疗中,实施中医药治疗具有较好的临床效果,且不良反应少。Objective To investigate the clinical effect of TCM syndrome differentiation in the treatment of patients with high risk of hormone receptor positive breast cancer.Methods A total of 60 patients with high risk of hormone receptors in breast cancer were enrolled in the hospital from February 2016 to February 2019.The 60 patients were randomly divided into observation group(n=30)and control group(n=30).The control group underwent endocrine therapy,and the patients in the observation group underwent TCM syndrome differentiation treatment.The treatment effects of the two groups were compared Results The one-year disease-free survival rate of the observation group was 90.00%(27/30),which was significantly higher than that of the control group(80.00%,24/30).The statistical difference was significant(х2=3.9216,P=0.0476).After treatment,the observation group had 1 case of leukopenia and 1 case of abnormal liver function.The incidence of adverse reactions was 6.67%.In the control group,there were 3 cases of leukopenia and 2 cases of abnormal liver function.The incidence of adverse reactions was 16.67%.The adverse reactions occurred in the observation group.The rate was significantly lower than that of the control group,and the statistical difference was significant(х2=4.8505,P=0.0276).Conclusion In the treatment of high-risk hormone receptor-positive patients after breast cancer surgery,the implementation of traditional Chinese medicine treatment has a good clinical effect,and less adverse reactions.

关 键 词：乳腺癌 激素受体 阳性 高危患者 中医辨证 乳岩 

分 类 号：R249[医药卫生—中医临床基础] R273[医药卫生—中医学]