山莨菪碱联合阿奇霉素对支原体肺炎患儿症状改善及免疫功能的影响  

Effects of anisodamine co mbined with azithromycin on improvement of symptoms and immune function in children with mycoplasma pneumonia

作　　者：陈玉婷 温秀曲 Chen Yuting;Wen Xiuqu(Dapu County People's Hospital,Meizhou Meizhou 514200,China)

机构地区：[1]梅州市大埔县人民医院,广东梅州514200

出　　处：《北方药学》2020年第7期141-142,共2页Journal of North Pharmacy

摘　　要：目的:探讨山莨菪碱联合阿奇霉素对支原体肺炎患儿症状改善及免疫功能的影响。方法:本次研究对象是我院于2017年3月—2019年5月接收的100例支原体肺炎患儿,采用随机数表法分为两组,各50例。对照组给予单一药物阿奇霉素治疗,观察组给予山茛菪碱联合阿奇霉素治疗,观察比较两组临床症状改善情况及免疫功能。结果:治疗后,观察组退烧、(肺部啰音、咳嗽、喘息)消失时间对比对照组,明显偏短,差异有统计学意义(P<0.05);治疗后,观察组免疫球蛋白G(IgG)、免疫球蛋白M(IgM)、免疫球蛋白A(IgA)水平均高于对照组,差异有统计学意义(P<0.05)。结论:临床在治疗支原体肺炎患儿时,应用山茛菪碱联合阿奇霉素效果较好,可以缩短症状改善时间,改善免疫功能,促进恢复。Objective:To investigate the effects of anisodamine combined with azithromycin on the improvement of symptoms and immune function in children with mycoplasma pneumonia. Methods:The subjects of this study were 100 children with mycoplasma pneumonia received in our hospital from March 2017 to May 2019. They were divided into 2 groups by random number table, 50 cases each. The control group was treated with a single drug azithromycin, and the observation group was treated with anisodamine combined with azithromycin. The clinical symptoms and immune function of the two groups were observed and compared. Results:After treatment, the time of disappearance of fever,(pulmonary rales, cough, wheezing) in the observation group was significantly shorter than that in the control group, and the results were significantly shorter(P<0.05). The levels of G(IgG), immunoglobulin M(IgM), and immunoglobulin A(IgA)were higher than those in the control group, and the differences were statistically significant(P <0.05). Conclusion:In the treatment of children with mycoplasma pneumonia, the application of anisodamine combined with azithromycin has a better effect, which can shorten the time to improve symptoms, improve its immune function, and promote recovery.

关 键 词：支原体肺炎 山茛菪碱 阿奇霉素 免疫功能 

分 类 号：R725.6[医药卫生—儿科]