肝内周围型胆管细胞癌的CT及MRI诊断与临床意义对照分析  

Comparative Analysis of CT and MRI Diagnosis and Clinical Significance of Intrahepatic Peripheral Cholangiocarcinoma

作　　者：温界玉 刘雨峰[1] 杨想春[2] 康彦智 马鸣岳[2] 马党捐[1] 张林凤 韦明炯[1] WEN Jie-yu;LIU Yu-feng;YANG Xiang-chun(Department of Imaging,The Second People's Hospital of Shaanxi Province,Xi'an 710005,Shaanxi Province,China)

机构地区：[1]陕西省第二人民医院影像科,陕西西安710005 [2]西安交通大学医学院附属西安市中心医院放射科,陕西西安710003

出　　处：《中国CT和MRI杂志》2020年第10期77-79,89,共4页Chinese Journal of CT and MRI

基　　金：陕西省社会发展科技攻关项目(编号:2016SF-129)。

摘　　要：目的探讨肝内周围型胆管细胞癌(Intrahepaticperipheral cholangiocarcinoma,HPCC)的CT及MRI诊断与临床意义对照分析。方法选取自2014年11月到2016年8月在我院就诊的68例疑似HPCC患者作为研究对象,所有研究对象入院后接受CT、MRI检查,并给予后期病理学诊断,其中45例为HPCC确诊患者,剩余23例为胆管下段良性肿瘤患者。比较CT、MRI联合检查和CT、MRI单独检查的灵敏度、特异度、阳性预测值、阴性预测值以及符合率。结果 CT检查的灵敏度为71.11%,特异度为73.91%,阳性预测值为84.21%,阴性预测值为56.67%,符合率为72.06%。MRI检查的灵敏度为75.56%,特异度为82.61%,阳性预测值为89.47%,阴性预测值为63.33%,符合率为77.94%。CT、MRI联合检查的灵敏度为91.11%,特异度为95.65%,阳性预测值为97.62%,阴性预测值为84.62%,符合率为92.65%。CT、MRI联合检查的灵敏度、特异度、阳性预测值、阴性预测值、符合率显著高于CT单独检查,灵敏度、符合率显著高于MRI单独检查,且以上差异具备统计学意义(P<0.05)。结论 CT、MRI联合检查对肝内周围型胆管细胞癌鉴别诊断效果较好,临床应用价值高。Objective To study the CT and MRI diagnosis and clinical significance of intrahepatic peripheral cholangiocarcinoma.Methods From November 2014 to August 2016,68 patients with suspected intrahepatic peripheral cholangiocarcinoma were selected as the study objects.All the subjects received CT and MRI examination after admission,and were given pathological diagnosis in the later stage.45 of them were diagnosed with intrahepatic peripheral cholangiocarcinoma,and the remaining 23 were benign tumor in the lower segment of the bile duct.The sensitivity,specificity,positive predictive value,negative predictive value and coincidence rate of CT,MRI combined examination and CT,MRI alone examination were compared.Results The sensitivity of CT was 71.11%,the specificity was 73.91%,the positive predictive value was 84.21%,the negative predictive value was 56.67%,and the coincidence rate was 72.06%.The sensitivity of MRI was 75.56%,the specificity was 82.61%,the positive predictive value was 89.47%,the negative predictive value was 63.33%,and the coincidence rate was 77.94%.The sensitivity of CT and MRI was 91.11%,the specificity was 95.65%,the positive predictive value was 97.62%,the negative predictive value was 84.62%,and the coincidence rate was 92.65%.The sensitivity,specificity,positive predictive value,negative predictive value and coincidence rate of CT and MRI combined examination were significantly higher than that of CT alone examination,and the sensitivity and coincidence rate were significantly higher than that of MRI alone examination,and the difference was statistically significant(P<0.05).Conclusion CT combined MRI has a good effect on differential diagnosis of intrahepatic peripheral cholangiocarcinoma,which is worthy of popularization and application.

关 键 词：肝内周围型胆管细胞癌 C T及MRI诊断 临床意义 

分 类 号：R445.2[医药卫生—影像医学与核医学] R445.3[医药卫生—诊断学]