血液滤过联合血液灌流救治急性重症农药中毒患者的效果研究  

The effect of hemofiltration combined with hemoperfusion in the treatment of acute severe pesticide poisoning

作　　者：邬艺渊 Wu Yiyuan(Department of Critical Medicine,the People's Hospital of Leshan City,Sichuan Leshan 614000)

机构地区：[1]乐山市人民医院重症医学科,四川乐山614000

出　　处：《中国社区医师》2020年第25期37-38,共2页Chinese Community Doctors

摘　　要：目的:研究血液滤过联合血液灌流治疗急性重症农药中毒的临床效果。方法:2016年1月-2019年10月收治急性重症有机磷农药中毒患者60例,随机分为两组。对照组采用常规治疗;试验组在常规治疗基础上予以血液滤过联合血液灌流治疗。比较两组治疗效果。结果:试验组发生中间综合征、反跳现象、多器官功能障碍及肺部感染等并发症发生率均低于对照组,差异有统计学意义(P<0.05),试验组治疗后炎性因子指标水平优于对照组,差异有统计学意义(P<0.05)。结论:采用血液滤过联合血液灌流治疗,有利于减少急性重症农药中毒患者并发症发生率、抑制炎性因子产生,确保临床疗效。Objective:To explore the effect of hemofiltration combined with hemoperfusion in the treatment of acute severe pesticide poisoning.Methods:From January 2016 to October 2019,60 patients with acute severe organophosphorus pesticide poisoning were selected and randomly divided into two groups.The control group was treated with routine treatment.The experimental group was treated with hemofiltration combined with hemoperfusion on the basis of conventional treatment.We compared the efficacy of the two groups.Results:In the experimental group,the incidence of complications such as intermediate syndrome,rebound phenomenon,multiple organ dysfunction and pulmonary infection was lower than that in the control group,the difference was statistically significant(P<0.05).In the experimental group,after treatment,the index of inflammatory factors was better than that of the control group,the difference was statistically significant(P<0.05).Conclusion:Hemofiltration combined with hemoperfusion can reduce the incidence of complications of acute severe pesticide poisoning,inhibit the production of inflammatory factors and ensure the clinical efficacy.

关 键 词：中毒 急性 血液滤过 血液灌流 重症 农药中毒 效果分析 

分 类 号：R595.4[医药卫生—内科学]