类风湿关节炎诊断中免疫学检验联合检测的应用价值  

The application value of immunological examination combined with detection in the diagnosis of rheumatoid arthritis

作　　者：郭旺源[1] 廖琳 林应标[1] 夏川[1] 熊丽 刘志超 Guo Wangyuan;Liao Lin;Lin Yingbiao;Xia Chuan;Xiong Li;Liu Zhichao(First People's Hospital of Chenzhou City,Hunan Chenzhou 423000)

机构地区：[1]郴州市第一人民医院,湖南郴州423000

出　　处：《中国社区医师》2020年第25期127-128,共2页Chinese Community Doctors

摘　　要：目的:探究免疫学检验联合检测在类风湿关节炎诊断中的应用价值。方法:2019年2月-2020年3月收治类风湿关节炎患者73例,作为观察组;选择同期健康体检者73例,作为对照组。两组均接受免疫学检验联合检测,比较两组诊断结果。结果:观察组类风湿因子(RF)、抗环瓜氨酸肽(CCP)抗体及抗角质蛋白抗体(AKA)发生率均高于对照组,差异有统计学意义(P<0.05)。观察组联合检测的阳性率高于对照组,差异有统计学意义(P<0.05)。观察组IgG水平高于对照组,补体C3和补体C4水平均低于对照组,差异有统计学意义(P<0.05)。结论:类风湿关节炎诊断中免疫学检验联合检测准确率较高,可为诊断提供有效依据。Objective:To explore the application value of immunological examination combined with detection in the diagnosis of rheumatoid arthritis.Methods:From February 2019 to March 2020,73 patients with rheumatoid arthritis were selected as observation group.73 cases of health checkups were selected for the same period as the control group.Immunological examination combined with detection were performed in both groups to compare the diagnostic results.Results:The incidence of rheumatoid factor(RF),anti-cyclic citrullinated peptide antibody(CCP)and anti-keratinin antibody(AKA)in the observation group was higher than the control group,and the differences were statistically significant(P<0.05).The positive rate of combined detection in the observation group was higher than the control group,and the difference was statistically significant(P<0.05).The IgG level of the observation group was higher than the control group,and the complement C3 and C4 levels were lower than the control group,and the differences were statistically significant(P<0.05).Conclusion:The diagnosis of rheumatoid arthritis in immunological examination combined with detection accuracy is high,which can provide an effective basis for the diagnosis.

关 键 词：类风湿关节炎 诊断 免疫学检验联合检测 

分 类 号：R593.22[医药卫生—内科学]