经皮冠状动脉介入治疗与药物治疗对急性心肌梗死患者预后的影响  

Effects of percutaneous coronary intervention and drug therapy on prognosis of patients with acute myocardial infarction

作　　者：张建勋 李海鹃 苏保华 张立立 周雪娥 ZHANG Jianxun;LI Haijuan;SU Baohua;ZHANG Lili;ZHOU Xue'e(Cardiovascular Medicine Department,the Hospital of Mian County,Hanzhong 724200,China)

机构地区：[1]陕西省勉县医院心血管内科,陕西汉中724200

出　　处：《临床医学研究与实践》2020年第25期56-58,共3页Clinical Research and Practice

摘　　要：目的比较经皮冠状动脉介入治疗(PCI)与药物治疗对急性心肌梗死患者预后的影响。方法回顾性分析我院2015年9月至2018年12月收治的60例急性心肌梗死患者的临床资料,根据治疗方式不同将其分为对照组(30例,药物溶栓治疗)和观察组(30例,PCI术治疗)。比较两组的血管再通情况、心功能指标、心肌酶水平及预后情况。结果观察组的血管再通率显著高于对照组,差异具有统计学意义(P<0.05)。治疗后,两组的LVEF均增加,LVEDD、LVESD均减小,且观察组显著优于对照组,差异具有统计学意义(P<0.05)。治疗后,两组的LDH、CK-MB、cTnI水平均降低,且观察组低于对照组,差异具有统计学意义(P<0.05)。观察组的不良心血管事件总发生率显著低于对照组,差异具有统计学意义(P<0.05)。结论与药物溶栓治疗相比,PCI治疗能够更有效地改善急性心肌梗死患者的心功能指标和心肌酶水平,提高血管再通率,并且治疗后1年内不良心血管事件发生率较低,预后更好。Objective To compare the effects of percutaneous coronary intervention(PCI)and drug therapy on prognosis of patients with acute myocardial infarction.Methods The clinical data of 60 patients with acute myocardial infarction treated in our hospital from September 2015 to December 2018 were retrospectively analyzed,and the patients were divided into control group(30 cases,drug thrombolytic treatment)and observation group(30 cases,PCI treatment)according to different treatment methods.The vascular recanalization,cardiac function indexes,myocardial enzyme levels and prognosis were compared between the two groups.Results The vascular recanalization rate of the observation group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,LVEF of the two groups increased,LVEDD and LVESD decreased,those in the observation group were significantly better than the control group,and the differences were statistically significant(P<0.05).After treatment,LDH,CK-MB,cTnIlevels of the two groups decreased,those in the observation group were lower than the control group,and the differences were statistically significant(P<0.05).The total incidence of adverse cardiovascular events in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Compared with drug thrombolytic therapy,PCI treatment can more effectively improve the cardiac function indexes and myocardial enzyme levels of patients with acute myocardial infarction,it can improve the vascular recanalization rate,and has lower incidence of adverse cardiovascular events within 1 year after treatment and better prognosis.

关 键 词：PCI 药物溶栓治疗 急性心肌梗死 预后 

分 类 号：R542.22[医药卫生—心血管疾病]