不同年龄段慢性阻塞性肺疾病患者戒烟后肺功能变化的比较  

Comparison of changes of pulmonary function in different ages of patients with chronic obstructive pulmonary disease after smoking cessation

作　　者：刘荆湖[1] 袁水生 胡平生[1] 邹小凡[1] 范家亮[1] LIU Jing-hu;YUAN Shui-sheng;HU Ping-sheng;ZOU Xiao-fan;FAN Jia-liang(Department of Respiratory Medicine,Ji′an Central People′s Hospital in Jiangxi Province,Ji′an,343100,China)

机构地区：[1]江西省吉安市中心人民医院呼吸科,江西吉安343100

出　　处：《中国当代医药》2020年第24期56-58,共3页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(20202110)。

摘　　要：目的探讨不同年龄段慢性阻塞性肺疾病(COPD)患者戒烟后肺功能的变化。方法回顾性收集2018年2月~2019年2月我院收治的60例COPD患者的临床资料,根据患者年龄进行分组,其中18~38岁为青年组,>38~59岁为中年组,>59岁为老年组,每组各20例。均予戒烟干预,比较三组戒烟前后肺功能[慢呼肺活量(SVC)、用力肺活量占预计值百分比(FVC%Pred)、第1秒用力呼气容积占预计值百分比(FEV1%Pred)及1秒率(FEV1/FVC%)]、生活质量(NHP评分)。结果戒烟后12个月,三组的SVC、FVC%Pred、FEV1%Pred、FEV1/FVC肺功能指标水平高于戒烟前,且青年组SVC、FVC%Pred、FEV1%Pred、FEV1/FVC高于中年组、老年组,差异均有统计学意义(P<0.05);青年组NHP评分高于中年组、老年组,中年组NHP评分高于老年组,差异有统计学意义(P<0.05)。结论戒烟干预对不同年龄段COPD患者均有一定效果,可有效改善患者肺功能,在疾病预防控制中有重要作用;同时提倡患者早期戒烟,可有效提高其生活质量。Objective To investigate the changes of pulmonary function in different ages of patients with chronic obstructive pulmonary disease(COPD)after smoking cessation.Methods The clinical data of 60 patients with COPD admitted to our hospital from February 2018 to February 2019 were retrospectively collected.All patients were divided into three groups according to the age of patients,18-38 years old was taken as youth group,>38-59 years old was taken as middle-aged group,and>59 years old was taken as senile group,20 cases in each group.All selected cases were given smoking cessation intervention,and the pulmonary function(slow vital capacity[SVC],forced vital capacity of percentage prediction[FVC%Pred],forced expiratory volume in one second of percentage prediction[FEV1%Pred],forced expiratory volume in one second/forced vital capacity[FEV1/FVC%])and quality of life(nottingham health profile[NHP])were compared among the three groups before and after smoking cessation.Results After smoking cessation for 12 months,the levels of pulmonary function indexes such as SVC,FVC%Pred,FEV1%Pred and FEV1/FVC in the three groups were higher than those before smoking cessation,and youth group was higher than middle-aged group and senile group,and the differences were statistically significant(P<0.05).The NHP score of youth group was higher than that of middle-aged group and senile group,and middle-aged group was higher than that of the senile group,and the differences were statistically significant(P<0.05).Conclusion Smoking cessation intervention for different ages of patients with COPD has certain effect,it can improve pulmonary function,prevent and control the diseases.At the same time,patients should be encouraged to early quit smoking to effectively improve their quality of life.

关 键 词：慢性阻塞性肺疾病 戒烟 肺功能 

分 类 号：R563.9[医药卫生—呼吸系统]