1454张门急诊泌尿系感染抗菌药物处方点评与分析  

Review and Analysis of 1454 Prescriptions of Antibiotics for Urinary Tract Infection in Outpatient and Emergency Department

作　　者：刘立丽[1] LIU Lili(Dept. of Pharmacy, Beijing Changping District Hospital of Integrated Traditional Chinese and Western Medicine, Beijing 102208, China)

机构地区：[1]北京市昌平区中西医结合医院药剂科,北京102208

出　　处：《中国医院用药评价与分析》2020年第8期1013-1016,共4页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:了解北京市昌平区中西医结合医院(以下简称“我院”)门急诊泌尿系感染患者的抗菌药物使用情况,为泌尿系感染合理用药提供参考。方法:采用回顾性分析方法,随机抽取2018年7月至2019年12月我院门急诊泌尿系感染抗菌药物处方1454张,进行点评与分析。采用Excel 2017软件进行统计分析,对部分内容进行帕累托图分析。结果:1454张门急诊泌尿系感染抗菌药物处方中,合理处方1382张,处方合理率为95.05%。2018年7—12月、2019年1—6月和2019年7—12月的处方不合理率分别为7.65%(42/549)、3.74%(14/374)和3.01%(16/531),呈降低趋势;抗菌药物联合应用处方所占比例由2018年7—12月的7.65%(42/549)降至2019年7—12月的3.95%(21/531);口服抗菌药物处方所占比例约为80%;限制使用级抗菌药物处方所占比例约为50%;氨基糖苷类抗菌药物处方所占比例由2018年7—12月的7.83%(43/549)降至2019年7—12月的2.64%(14/531)。不合理处方共72张,其中用药不适宜处方70张(75例次),包括适应证不适宜17例次,遴选药品不适宜14例次,剂型或给药途径不适宜8例次,用法、用量不适宜31例次以及联合用药不适宜5例次。讨论:专项点评工作促进了我院泌尿系感染抗菌药物的合理应用,联合用药处方明显减少,氨基糖苷类抗菌药物的使用日趋规范,但抗菌药物使用级别过高等问题仍需持续改进。OBJECTIVE:To investigate the application of antibiotics for urinary tract infection in outpatient and emergency department in Beijing Changping District Hospital of Integrated Traditional Chinese and Western Medicine(hereinafter referred to as“our hospital”),so as to provide reference for the rational application of antibiotics.METHODS:Retrospective analysis was used,from Jul.2018 to Dec.2019,1454 prescriptions of antibiotics for urinary tract infection in the outpatient and emergency department of our hospital were randomly selected for review and analysis.Excel 2017 software was used for statistical analysis,and Pareto chart analysis was performed on part of the contents.RESULTS:Among the 1454 prescriptions of antibiotics for urinary tract infection,1382 were rational prescriptions,and the rational rate was 95.05%.The irrational rate of prescriptions from Jul.to Dec.2018,from Jan.to Jun.2019 and from Jul.to Dec.2019 were respectively 7.65%(42/549),3.74%(14/374)and 3.01%(16/531),showing the decreasing trend.The proportion of prescriptions for drug combination of antibiotics decreased from 7.65%(42/549)from Jul.to Dec.2018 to 3.95%(21/531)from Jul.and Dec.2019.Application of oral antibiotics accounted for 80%,and restricted antibiotics accounted for 50%.The proportion of aminoglycosides dropped from 7.83%(43/549)from Jul.to Dec.2018 to 2.64%(14/531)from Jul.to Dec.2019.There were 72 irrational prescriptions,of which 70 prescriptions(75 case-times)were inappropriate prescriptions,including 17 case-times of inappropriate indications,14 case-times of inappropriate selection of drugs,8 case-times of improper dosage forms or route of administration,31 case-times of improper usage and dosage,and 5 case-times of improper drug combination.CONCLUSIONS:The prescription-review project has promoted the rational application of antibiotics for urinary tract infection in our hospital.The prescription of drug combination has been significantly reduced,and the application of aminoglycosides has become more standardized,yet pr

关 键 词：泌尿系感染 抗菌药物 分析 不合理用药 

分 类 号：R978.31[医药卫生—药品]