Clinical observation on herb-partitioned spreading moxibustion at Baliao points plus climen for diminished ovarian reserve  

八髎穴中药铺灸加克龄蒙治疗卵巢储备功能下降的临床观察

作　　者：Chen Li Wan Dan Fan Zheng-peng Xia Min Duan Ya-ting 陈丽;万丹;范正鹏;夏敏;段亚亭;张馥晴(翻译)(Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China;不详)

机构地区：[1]Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China

出　　处：《Journal of Acupuncture and Tuina Science》2020年第4期262-268,共7页针灸推拿医学（英文版）

基　　金：重庆市科研机构绩效激励引导专项项目,No.cstc2018jxj1130059.

摘　　要：Objective:To observe the clinical efficacy of herb-partitioned spreading moxibustion at Baliao points plus climen for diminished ovarian reserve(DOR).Methods:A total of 60 patients with DOR were randomized into a spreading moxibustion group and a Western medicine group by the random number table method,with 30 cases in each group.The Western medicine group was treated with climen,starting from the 5th day of the menstrual cycle for 21 d.The spreading moxibustion group was treated with herb-partitioned spreading moxibustion at Baliao points on the basis of the medication in the Western medicine group,1 h per time,once a week.The treatment was performed for 1 month as one treatment course in both groups,for 3 courses in total.The serum follicle-stimulating hormone(FSH),luteinizing hormone(LH)and estradiol(E2)in the patients were measured before and after treatment.The peak systolic velocity(PSV)and resistance index(RI)were also detected.The traditional Chinese medicine(TCM)symptom score was evaluated.The clinical efficacy was evaluated after treatment.Results:The total effective rate in the spreading moxibustion group was 93.3%,which was significantly higher than 80.0%in the Western medicine group,and the difference between the groups was statistically significant(P<0.05).After treatment,the TCM symptom scores,the serum FSH levels,FSH/LH ratios and RI in both groups decreased,and the intra-group differences were all statistically significant(all P<0.05).The serum E2 level and PSV increased compared with those in the same group before treatment,and the intra-group differences were statistically significant(all P<0.05).After treatment,the TCM symptom score,the serum FSH level,FSH/LH ratio and RI in the spreading moxibustion group were lower than those in the Western medicine group,while the serum E2 level and PSV were higher than those in the Western medicine group,and the differences between the groups were statistically significant(all P<0.05).Conclusion:Herb-partitioned spreading moxibustion at Baliao points plus 目的:观察八髎穴中药铺灸加克龄蒙治疗卵巢储备功能下降(DOR)的临床疗效.方法:将60例DOR患者按随机数字表法分为铺灸组和西药组,每组30例.西药组予克龄蒙治疗,月经周期第5 d开始服用,连用21 d;铺灸组在克龄蒙治疗基础上加用中药铺灸八髎穴,每次约1 h,每周1次.两组均以1个月为1个疗程,治疗3个疗程.治疗前后检测血清促卵泡生成素(FSH)、黄体生成素(LH)和雌二醇(E2)含量,测定血流收缩期峰值流速(PSV)及阻力指数(RI),评定中医症状积分.治疗后评价临床疗效.结果:铺灸组的总有效率为93.3%,高于西药组的80.0%,组间差异有统计学意义(P<0.05).治疗后,两组中医症状积分,血清FSH水平、FSH/LH值及RI均较治疗前下降,组内差异均有统计学意义(均P<0.05),血清E2水平及PSV均较治疗前升高,组内差异均有统计学意义(均P<0.05).治疗后,铺灸组中医症状积分及血清FSH水平、FSH/LH值及RI均低于西药组,血清E2水平及PSV均高于西药组,组间差异均有统计学意义(均P<0.05).结论:八髎穴中药铺灸加克龄蒙治疗DOR疗效确切,可改善临床症状,调节血清激素水平,增加卵巢血流灌注,进而改善卵巢储备功能,其疗效优于单独克龄蒙治疗.

关 键 词：Moxibustion Therapy Indirect Moxibustion Points Baliao Gonadal Steroid Hormones Diminished Ovarian Reserve Ovarian Reserve Women 

分 类 号：R246.3[医药卫生—针灸推拿学]