宫颈癌患者的膀胱充盈度一致性对放疗摆位误差的影响  

Effect of consistency of bladder filling volume on set-up errors in radiotherapy for the patients with cervical cancer

作　　者：李钰[1] 高岩[1] 刘世龙 董丽华[1] 夏诚诚 LI Yu;GAO Yan;LIU Shilong;DONG Lihua;XIA Chengcheng(Department of Radiotherapy,First Hospital of Jilin University,Changchun 130021 China)

机构地区：[1]吉林大学第一医院放疗科,吉林长春130021

出　　处：《中国辐射卫生》2020年第3期305-308,共4页Chinese Journal of Radiological Health

摘　　要：目的研究宫颈癌患者的膀胱充盈度一致性对于精准放疗摆位的重要性。方法选取宫颈癌患者30例,随机分为观察组和对照组;观察组在CT定位前,利用膀胱容量测定仪测定膀胱充盈度,每次治疗时膀胱容量达到定位容量时再放疗;对照组自主憋尿后行定位及放疗。每周1次CBCT扫描,分别测得患者左右、背腹和头脚方向的摆位误差。结果观察组和对照组在左右、背腹、头脚三个方向上摆位误差分别为(1.71±0.48)mm、(1.43±0.68)mm、(1.97±0.52)mm和(1.79±0.54)mm、(1.61±0.80)mm、(3.10±1.01)mm。观察组头脚方向摆位误差明显小于对照组(t=–3.837,P<0.05);通过摆位误差计算出的外扩边界分别为4.611 mm、4.051 mm、5.289 mm和4.853 mm、4.585 mm、8.457 mm,观察组在头脚方向明显优于对照组。结论宫颈癌患者的膀胱充盈度一致性有利于减少放疗时的摆位误差,减少外扩和正常组织受照,因此有助于精准治疗。Objective To study the importance of the consistency of bladder filling volume to the accuracy of radiotherapy positioning for patients with cervical cancer.Methods 30 patients with cervical cancer were randomly divided into two groups,the observation group and the control group.Before CT localization,the bladder filling volume of patients in the observation group was measured by bladder scanner.Radiotherapy was performed when the bladder volume was reached the fixed volume.Patients in the control group received radiotherapy immediately after spontaneous bladder control.CBCT scan was performed to measure set-up errors on directions of left/right,dorsal/ventral,and head/foot,respectively.Results In the three directions of left/right,dorsal/ventral,and head/foot,the set-up errors of the observation group and control group were(1.71±0.48)mm,(1.43±0.68)mm,(1.97±0.52)mm and(1.79±0.54)mm,(1.61±0.80)mm,(3.10±1.01)mm.The set-up errors of head/foot direction of patients in the observation group were significantly smaller than that of patients in the control group(t=−3.837,P<0.05).The outspread boundary calculated by positioning errors were 4.611 mm、4.051 mm、5.289 mm and 4.853 mm、4.585 mm、8.457 mm,respectively.The head and foot direction of the observation group is significantly better than that of the control group.Conclusion The consistency of bladder filling volume of patients with cervical cancer is good to improve radiotherapy positioning accuracy,reduce the external expansion and exposure of normal tissue,which can help accurate radiotherapy.

关 键 词：宫颈癌 放射治疗 膀胱充盈度 摆位误差 

分 类 号：R816.91[医药卫生—放射医学]