准分子激光联合药涂球囊治疗下肢动脉硬化闭塞的临床疗效分析  

Excimer laser combined with drug coated balloon in the treatment of arteriosclerosis obliterans of lower extremities

作　　者：谷岩[1] 何菊[1] 刘辉[1] Gu Yan;He Ju;Liu Hui(Department of Vascular Surgery,the First Central Hospital of Tianjin,Tianjin 300192,China.)

机构地区：[1]天津市第一中心医院血管外科,300192

出　　处：《中华普通外科杂志》2020年第8期640-643,共4页Chinese Journal of General Surgery

基　　金：天津市卫生局科技基金项目(2015KZ033)。

摘　　要：评价准分子激光消融术(ELA)联合药物涂层球囊(DCB)血管成形术腔内治疗下肢动脉硬化闭塞血管的有效性、安全性.方法回顾性分析2017年5至12月在天津市第一中心医院因下肢动脉闭塞疾病接受ELA治疗的17例患者的基本特征和临床资料,包括12个月的一期通畅率、技术成功率、手术成功率、支架置入率、靶血管再次干预率和主要不良事件.结果平均病变长度(23.3±8.9)cm.手术成功率100%,均行辅助性DCB治疗.5例行支架置入,12个月一期通畅率为82.4%.靶病变复发率为5.9%.结论ELA联合DCB治疗下肢动脉闭塞疾病安全可行.Objective To evaluate the efficacy and safety of excimer laser ablation(ELA)combined with drug-eluting balloon angioplasty in the treatment of arteriosclerosis obliterans of lower extremities.Methods The clinical data of 17 patients who received ELA from May to Dec 2017 was retrospectively analyzed,including 12-month primary patency rate,technical success rate,surgical success rate,stent implantation rate,target vessel reintervention rate and major adverse events.Results The length of lesions was(23.3±8.9)cm.The success rate of technique and operation was 100%.All cases were treated with combined DCB.Five cases underwent stent placement,and the patency rate at 12 months was 82.4%.The recurrence rate of target lesion was 5.9%.Conclusion ELA combined with DCBA is safe and feasible in the treatment of lower extremity arterial occlusive disease.

关 键 词：激光 准分子 闭塞性动脉硬化 斑块切除术 药物涂层球囊 血管成形术 

分 类 号：R654.4[医药卫生—外科学]