相对淋巴细胞计数与老年重度COPD患者3年病死率的相关性分析  

Correlation between Lymphocyte Count and 3-year Mortality in Elderly Patients with Severe COPD

作　　者：吴劲松 张艳 张怀中 WU Jin-song;ZHANG Yan;ZHANG Huai-zhong(Department of Geriatrics,Xuzhou Third People's Hospital,Xuzhou Jiangsu,221005)

机构地区：[1]徐州市第三人民医院老年科,江苏徐州221005

出　　处：《医学临床研究》2020年第8期1192-1194,共3页Journal of Clinical Research

摘　　要：【目的】探讨相对淋巴细胞计数(L%)与老年慢性阻塞性肺疾病(COPD)患者3年病死率的相关性。【方法】选取2015年8月至2016年8月在本院诊治的69例COPD患者,按L%分为A组(L%≤20%)和B组(L%>20%),收集所有患者的临床资料,出院后均随访3年,比较两组患者的一般资料,分析L%与3年病死率间的相关性。【结果】69例患者中,A组27例,占39.13%;B组42例,占60.87%。A组患者3年病死率为81.48%(22/27),显著高于B组的57.14%(24/42),其差异有统计学意义(P<0.05)。对年龄和性别进行调整后,死亡危险度为1.88(95%置信区间CI:1.21-2.56,P<0.01)。【结论】L%≤20%的3年重度COPD患者病死率较高,提示L%是预测老年COPD患者预后的指标。【Objective】To evaluate the correlation between the relative lymphocyte count(L%)and the 3-year mortality in elderly patients with COPD.【Methods】A total of 69 patients with chronic obstructive pulmonary disease(COPD)in our hospital from August 2015 to August 2016 were selected for the study.Patients were divided into two groups according to the relative lymphocytes count.Group A was the relative lymphocyte count≤20%and the group B was the relative lymphocyte count>20%.The general data of the two groups were collected,all patients were followed up for 3 years after discharge.Thus the general data of the two groups were compared and the relationship between the relative lymph count and the 3-year mortality rate was analyzed.【Results】Among 69 patients,27(39.13%)patients had the relative lymphocyte count≤20%(group A),and 42(60.87%)patients had the relative lymphocyte count>20%(group B).The 3-year mortality rates of patients in the group A and group B were 81.48%(22/27)and 57.14%(24/42),respectively(P<0.05).The survival curve analysis showed that the mortality of patients with relative lymphocytes count≤20%was higher;And the difference was statistically significant(P<0.05).After adjusting for age and gender the risk of death was 1.88[95%confidence interval CI:1.21-2.56,P<0.01].【Conclusion】Lower relative lymphocyte count is associated with higher mortality in elderly patients with severe COPD.This result suggests that relative lymphocyte count can predict the prognosis of elderly patients with severe COPD.

关 键 词：肺疾病 慢性阻塞性 淋巴细胞计数 老年人 死亡率 

分 类 号：R692[医药卫生—泌尿科学]