隔姜灸联合补肾健脾方治疗慢性肾小球肾炎的效果研究  

Effect of Ginger Moxibustion Combined with Bushen Jianpi Recipe on Chronic Glomerulonephritis

作　　者：庞欣[1] 张建伟[1] 王学敏[1] PANG Xin;ZHANG Jianwei;WANG Xuemin(Department of Nephropathy,Henan Province Hospital of Traditional Chinese Medicine,The Second Affiliated Hospital of Henan University of Traditional Chinese medicine,Zhengzhou 450002,Henan,China)

机构地区：[1]河南中医药大学第二附属医院,河南省中医院肾病科,河南郑州450002

出　　处：《中华中医药学刊》2020年第8期254-258,共5页Chinese Archives of Traditional Chinese Medicine

基　　金：河南省高等学校重点科研项目(17A360003)。

摘　　要：目的探讨隔姜灸联合补肾健脾方治疗慢性肾小球肾炎的临床效果。方法选择2016年8月-2018年1月医院治疗的慢性肾小球肾炎患者98例,按照随机数字的方法分为对照组和观察组,每组49例,对照组在西医常规方法基础上给予补肾健脾方治疗,观察组在对照组处理方法基础上给予隔姜灸治疗,对两组治疗前后的主要症状中医评分,24 h尿蛋白,尿沉渣红细胞计数情况进行比较,对治疗效果和不良反应情况进行比较。结果经过治疗后,对照组的水肿症状评分从(5.31±0.51)分降低到(3.62±0.41)分,腰膝酸软症状评分从(4.61±0.62)分降低到(2.64±0.47)分,神疲乏力症状评分从(4.41±0.46)分降低到(2.27±0.29)分,畏寒肢冷症状评分从(4.37±0.34)分降低到(2.83±0.31)分,观察组的水肿症状评分从(5.42±0.37)分降低到(2.11±0.23)分,腰膝酸软症状评分从(4.73±0.46)分降低到(1.73±0.21)分,神疲乏力症状评分从(4.45±0.37)分降低到(1.67±0.19)分,畏寒肢冷症状评分从(4.41±0.37)分降低到(1.47±0.13)分,观察组的变化幅度大于对照组,数据差异均具有统计学意义(t=22.484,12.374,12.114,28.32,P<0.05),经过治疗后,对照组的24 h尿蛋白从(1.57±0.31)g降低到(1.11±0.28)g,尿沉渣红细胞计数从(10.55±1.92)个/HP降低到(7.16±1.16)个/HP,观察组的24 h尿蛋白从(1.58±0.38)g降低到(0.53±0.27)g,尿沉渣红细胞计数从(11.03±2.17)个/HP降低到(4.01±0.81)个/HP,观察组的变化幅度大于对照组,数据差异均具有统计学意义(t=10.438,15.585,P<0.05),观察组的治疗效果优于对照组,数据差异具有统计学意义(z=-5.209,P<0.05),两组的皮疹[2.04%(1/49)vs.6.12%(3/49)],消化道反应[6.12%(3/49)vs.10.20%(5/49)],头晕[10.20%(5/49)vs.14.29%(7/49)],瘙痒[16.33%(8/49)vs.14.26%(7/49)]的发生率数据差异均不具有统计学意义(χ~2=0.261,0.136,0.380,0.079,P>0.05)。结论使用隔姜灸联合补肾健脾方治疗慢性肾小球肾炎的患者,可以缓解患者的症状Objective To explore the clinical effect of ginger moxibustion combined with Bushen Jianpi Recipe in the treatment of chronic glomerulonephritis.Methods Ninety-eight patients with chronic glomerulonephritis treated in hospital from August 2016 to January 2018 were selected.They were randomly divided into control group and observation group,with 49 patients in each group.Patients in the control group were given Bushen Jianpi Recipe on the basis of conventional Western medicine,while patients in the observation group were given ginger moxibustion on the basis of the treatment of the control group.Before and after treatment,the main symptoms of traditional Chinese medicine score,24 hours urinary protein,urinary sediment red blood cell count of the two groups were compared.The therapeutic effects and adverse reactions were compared.Results After treatment,the edema symptom score of the control group decreased from(5.31±0.51)points to(3.62±0.41)points,and the waist and knee soreness score decreased from(4.61±0.62)points to(2.64±0.47)points.The spirit fatigue score decreased from(4.41±0.46)points to(2.27±0.29)points,and the cold limbs score decreased from(4.37±0.34)points to(2.83±0.31)points.The edema symptom scores of the observation group patients reduced from(5.42±0.37)points to(2.11±0.23)points,and the waist and knee soreness score decreased from(4.73±0.46)points to(1.73±0.21)points,and the score of spirit fatigue symptoms decreased from(4.45±0.37)points to(1.67±0.19)points.The score of cold limbs decreased from(4.41±0.37)points to(1.47±0.13)points,and the change of the observation group was larger than that of the control group.The data was statistically significant after treatment(t=22.484,12.374,12.114,28.32,P<0.05).The 24 h urine protein of the control group decreased from(1.57±0.31)g to(1.11±0.28)g,and the urine sediment red blood cell count decreased from(10.55±1.92)/HP to(7.16±1.16)/HP.The 24 h urine protein in the observation group decreased from(1.58±0.38)g to(0.53±0.27)g,and the urin

关 键 词：隔姜灸 补肾健脾方 慢性肾小球肾炎 

分 类 号：R269.923[医药卫生—中西医结合] R245.8[医药卫生—中医外科学]