新生女婴尿道旁腺囊肿诊治并文献分析  

Management of paraurethral cysts in female neonates with a literature review

作　　者：赵伟[1,2] 严宗逊 马学[1] Zhao Wei;Yan Zongxun;Ma Xue(Department of Pediatric Urology,West China Hospital,Sichuan University,Chengdu,610041,China;Department of Endocrinology,Affiliated Hospital,North Sichuan Medical College,Nanchong 637000,China)

机构地区：[1]四川大学华西医院小儿泌尿外科,四川省成都市610041 [2]川北医学院附属医院内分泌科,四川省南充市637000

出　　处：《临床小儿外科杂志》2020年第9期837-841,共5页Journal of Clinical Pediatric Surgery

基　　金：四川省科技计划项目资助项目(编号:2018SZ0392)。

摘　　要：目的总结新生女婴尿道旁腺囊肿的临床表现、诊断与鉴别诊断要点以及治疗方案的选择。方法随访2例新生女婴尿道旁腺囊肿病例,对其临床表现、转归进行评价;以“新生儿”、“女婴”、“尿道旁腺囊肿”、“Paraurethral cyst”、“Skene s duct”、“neonate,newborn”为检索词,检索PubMed数据库、中国知网、万方数据库、中国生物医学文献数据库以及维普数据库截至2019年2月公开发表的文献资料,并进行整理分析。结果2例均因生后发现尿道口包块就诊,无排尿困难,影像学检查提示尿道旁腺囊肿可能;随访期间包块逐渐消失,后期未见复发。通过文献检索,最终纳入8篇病例报道,含新生女婴尿道旁腺囊肿27例,加上本文报道的2例,共29例。其中无症状患儿共23例,13例选择随访观察,10例选择外科手术治疗;6例存在排尿异常、肿块增大等临床表现,1例选择临床观察,另外5例选择手术治疗。结论新生女婴尿道旁腺囊肿在临床上较罕见,但多数预后理想,并伴随有自然的缓解过程。Objective To summarize the symptom,diagnosis,differential diagnosis and treatment of paraurethral cysts in female neonates.Methods Two cases of female neonates with paraurethral cysts were followed up and their symptoms,outcomes and prognoses evaluated.The reports published before February,2019 were searched within the databases of PubMed,CNKI,Wangfang,CBMdisc and Weipu using MeSH terms of“paraurethral cyst”,“Skene s duct”,“neonate,newborn”.Results Two female neonates presented with urethral mass and non-dysuria.Imaging examination hinted at a possibility of developing paraurethral cyst.Mass disappeared gradually and no recurrence was noted during follow-ups.The authors selected 8 international literatures with an analysis of paraurethral cysts in female neonates.Among a total of 29 cases were summarized.Among 23 asymptomatic neonates,13 were selected for clinical observations and 10 underwent surgical interventions.As for 6 children with abnormal urination and mass enlargement,1 case was selected for clinical observation while the remainders were operated.Conclusion Female neonates with paraurethral cysts are clinically rare and relatively benign.And there is also a high frequency of spontaneous regression.

关 键 词：尿道旁腺 囊肿 新生儿 女性 

分 类 号：R726.9[医药卫生—儿科] R722[医药卫生—临床医学]