原发性甲状旁腺功能亢进症术后高钙危象一例  

One case of hypercalcemic crisis after parathyroidectomy in primary hyperparathyroidism

作　　者：张颖超 邓先兆[1] 郭伯敏[1] 伍波[1] 侯建忠 章振林[2] 高许萍[3] 樊友本[1] Zhang Yingchao;Deng Xianzhao;Guo Bomin;Wu Bo;Hou Jianzhong;Zhang Zhenlin;Gao Xuping;Fan Youben(Department of General Surgery,Thyroid and Parathyroid Center,Shanghai Jiao Tong University Affiliated Sixth People’s Hospital,Shanghai 200233,China;Department of Osteoporosis and Bone Disease,Metabolic Bone Disease and Genetics Research Unit,Shanghai Jiao Tong University Affiliated Sixth People’s Hospital,Shanghai 200233,China;Department of Nephrology,Shanghai Jiao Tong University Affiliated Sixth People’s Hospital,Shanghai 200233,China)

机构地区：[1]上海交通大学附属第六人民医院普外科,上海交通大学甲状腺疾病诊治中心,200233 [2]上海交通大学附属第六人民医院骨质疏松和骨病专科,骨代谢病和遗传研究室,200233 [3]上海交通大学附属第六人民医院肾脏科,200233

出　　处：《中华内分泌外科杂志》2020年第4期347-349,共3页Chinese Journal of Endocrine Surgery

基　　金：国家自然科学基金(81670718);上海交通大学优秀专病诊治中心资助基金(2014年4号)。

摘　　要：高钙危象(hypercalcemic crisis,HC)是一种少见但危急的电解质紊乱,危害心血管、神经系统和肾脏等,抢救不正确及时,可危及患者生命。HC多见于严重的原发性甲状旁腺功能亢进症(primary hyperparathyroidism,PHPT),通过限期手术切除病灶多可治愈。而成功的甲状旁腺切除术后再次出现高钙危象则罕见。本文报道上海交通大学附属第六人民医院普外科于2019年9月收治的1例PHPT治愈术后高钙危象成功抢救的病例,旨在引起临床医生对PHPT术后血钙个体化管理的重视,同时强调肾脏透析治疗在高钙危象抢救中的价值。Hypercalcemic crisis(HC)is a rare but critical electrolyte disorder,which may result in death if rapid correct management is not given due to the injury of the neurologic,cardiovascular and renal systems.Severe primary hyperthyroidism(PHPT)is listed as the most common cause of hypercalcemic crisis.Prompt surgical removal of the parathyroid glands is the most effective cure for HC.Nevertheless,hypercalcemic crisis after a successful parathyroidectomy is infrequent.Now,we report a case admitted to the Department of General Surgery of the Shanghai Jiao Tong University Affiliated Sixth People’s Hospital about a successful therapy of hypercalcemic crisis postparathyroidectomy in Sep.2019,aiming to remind clinicians of the individualized program of calcium supplement after surgery of hyperparathyroidism and emphasize the value of renal dialysis in HC.

关 键 词：高钙危象 原发性甲状旁腺功能亢进症 肾透析 甲状旁腺切除术 

分 类 号：R653[医药卫生—外科学] R736.1[医药卫生—临床医学]