硬化性黏液水肿1例  

A Case of Scleromyxedema

作　　者：张晗 冯永芳[1] 刘雯[1] 黄萌[1] 庹梅 邹亮[1] 陈柳青[1] ZHANG Han;FENG Yongfang;LIU Wen;HUANG Meng;TUO Mei;ZOU Liang;CHEN Liuqing(Department of Dermatology,Wuhan No.1 Hospital,Wuhan 430022,China)

机构地区：[1]武汉市第一医院皮肤科,湖北武汉430022

出　　处：《中国皮肤性病学杂志》2020年第9期1064-1066,共3页The Chinese Journal of Dermatovenereology

摘　　要：患者女,43岁,全身泛发性丘疹、硬化伴瘙痒1年半。皮损组织病理示:真皮内黏蛋白沉积,阿辛兰染色阳性;免疫固定电泳:IgG(+),轻链λ(+);骨髓细胞学检查未见明显异常。诊断:硬化性黏液水肿。A 43-year-old female presented generalized papules,sclerosis and pruritus for one and a half years.Histopathology examination revealed mucin deposition in the dermis,accompanied by positive alcian blue staining.Immunofixation electrophoresis showed positive of immunoglobulin G and λ light chain.There were no obvious abnormalities in bone marrow cytology examination.Therefore,the patient was diagnosed as scleromyxedema.

关 键 词：硬化性黏液水肿 黏蛋白 副球蛋白 

分 类 号：R758.6[医药卫生—皮肤病学与性病学]