云南省65例片形吸虫病临床特点  

Clinical features of 65 cases of fascioliasis in Yunnan Province

作　　者：李芹翠 陈凤 顾伟[2] 杨磊 LI Qin-cui;CHEN Feng;GU Wei;YANG Lei(Research Institute of Schistosomiasis Control in Dali Prefecture,Dali 671000,China;Affiliated Hospital of Dali University,Dali 671000,China;Dali Prefecture People’s Hospital,Dali 671000,China)

机构地区：[1]云南省大理州血吸虫病防治研究所,大理671000 [2]大理学院附属医院,大理671000 [3]大理州人民医院,大理671000

出　　处：《中国寄生虫学与寄生虫病杂志》2020年第4期521-523,共3页Chinese Journal of Parasitology and Parasitic Diseases

基　　金：云南省高层次卫生健康技术人才培养专项经费(媒介生物控制学H-2018072);卫生部寄生虫病原与媒介生物学重点实验室开放课题(No.WSBKTKT-201602)。

摘　　要：收集2011年11月-2018年11月云南省6地(市)片形吸虫病病例的临床资料。65例病例中,男28例,女37例。职业以农民为主,占64.6%(42/65),民族以汉族为主,占89.2%(58/65),病例主要来自大理地区,占72.3%(47/65)。65例病例均食过凉拌生菜,6例喝过生的山沟箐水。18例涉及5户家庭,有家庭聚集现象。全部病例均因不同程度发热、腹痛等就诊,血常规均提示嗜酸粒细胞增高,腹部彩超或CT (和/或)MRI检查结果示,以肝脏为主不同程度的脏器损害;粪检片形吸虫卵阳性率23.1%(15/65),血清片形吸虫抗体检测强阳性58例,阳性7例,阳性率100%(65/65)。全部病例经三氯苯达唑治疗后发热、腹痛明显好转,血常规嗜酸粒细胞、肝脏等病变也恢复正常。Clinical data of fascioliasis patients recorded in 6 prefectures(cities) in Yunnan Province were collected from November 2011 to November 2018.A total of 65 cases were enrolled,including 28 males and 37 females.The majority of them were farmers(64.6%,42/65),being Han ethnicity(89.2%,58/65),and coming from Dali District(72.3%,47/65).All of the 65 cases had eaten raw vegetables,and 6 of them had drunk unboiled gully water.Eighteen cases involving 5 families had family aggregative phenomenon.All the cases visited hospital for suffering fever and abdominal pain.Blood routine tests showed increased eosinophilia;abdominal color ultrasound scanning or CT(and/or) MRI examination suggested varying degrees of organ lesion particularly in the liver;and fecal sample examination revealed a positive rate of Fasciola eggs of 23.1%(15/65).The test for serum antibody against Fasciola found 58 strongly positive and 7 positive,resulting in a positive rate of 100%(65/65).All of the cases showed obvious improvement in symptoms of fever and abdominal pain after treatment with trichlorobendazole,and blood routine tests showed that eosinophils and liver lesions gradually returned to normal.

关 键 词：片形吸虫 脏器损害 三氯苯达唑 血清抗体 

分 类 号：R532.23[医药卫生—内科学]