超声引导下胸椎旁神经阻滞对肺的保护作用研究进展  

Research Progress in Protective Effects of Ultrasound-Guided Thoracic Paravertebral Block on Lungs

作　　者：罗小丹 杨堃[1] LUO Xiaodan;YANG Kun(Department of Anesthesiology,the First Affiliated Hospital of Kunming Medical University,Kunming 650032,China)

机构地区：[1]昆明医科大学第一附属医院麻醉科,昆明650032

出　　处：《医学综述》2020年第17期3486-3490,3495,共6页Medical Recapitulate

基　　金：国家自然科学基金(81760348)。

摘　　要：近年来,超声引导下胸椎旁神经阻滞(TPVB)已广泛应用于临床。炎症、氧化应激、创伤、缺血再灌注损伤等均可引起肺损伤,超声引导下TPVB具有抑制机体炎症反应、抗氧化应激反应、促进肺部氧合、减少术后肺部并发症、改善术后肺功能等作用。其在手术麻醉中具有操作简便、穿刺成功率高、穿刺并发症少、围手术期镇痛效果确切、对呼吸循环影响小的临床优势,对术中肺组织起到保护作用,未来可能在胸外科手术麻醉中发挥更大的作用。In recent years,thoracic paravertebral block(TPVB)has been widely used in clinic.Inflammation,oxidative stress,trauma,ischemia-reperfusion injury can all cause lung injury,and the ultrasound-guided TPVB can inhibit the inflammatory response and antioxidant stress response,promote lung oxygenation,reduce postoperative pulmonary complications,improve postoperative pulmonary function and so on.Moreover,TPVB has the advantages of simple operation,high success rate of puncture,less complications of puncture,affirmative analgesic effect in perioperative period,and little effect on respiratory circulation protecting lung tissue during operation,and may play a greater role in anesthesia of thoracic surgery in the future.

关 键 词：胸椎旁神经阻滞 超声引导 炎症反应 应激反应 肺功能 肺部并发症 

分 类 号：R614.4[医药卫生—麻醉学]