醋酸钙和维生素D治疗骨质疏松症的研究  

Study on the Treatment of Osteoporosis with Calcium Acetate and Vitamin D

作　　者：蔡学峰 沈晓峰[1] CAI Xue-feng;SHEN Xiao-feng(Department of Orthopedics and Traumatology,Chinese Medicine Hospital of Suzhou,Suzhou,Jiangsu Province,215009 China)

机构地区：[1]江苏省苏州市中医医院骨伤科,江苏苏州215009

出　　处：《中外医疗》2020年第19期100-101,110,共3页China & Foreign Medical Treatment

摘　　要：目的探讨醋酸钙和维生素D治疗骨质疏松症的疗效和安全性。方法方便选取2017年8月—2019年8月该院96例骨质疏松症患者,随机分为治疗组和对照组各48例。治疗时间为24周。治疗组给予醋酸钙和维生素D,每日1剂;对照组服用阿仑膦酸钠片。比较两组患者治疗后的预防效果、下腰痛LBOS评分和不良反应发生情况。结果治疗组的预防效果为(95.83%),明显优于对照组(75.00%)(χ^2=16.941,P<0.01);治疗组治疗后LBOS评分为(60.4±11.9)分,明显高于对照组的(55.6±10.8)分(t=2.720,P<0.01);治疗组各种不良反应的发生均较对照组少(P<0.05)。结论醋酸钙和维生素D能有效提高老年骨质疏松症患者骨密度、改善临床症状,同时具备良好的安全性。Objective To explore the efficacy and safety of calcium acetate and vitamin D in the treatment of osteoporosis.Methods Convenient select from August 2017 to August 2019,96 patients with osteoporosis were randomly divided into a treatment group and a control group of 48 patients.The treatment time is 24 weeks.The treatment group was given calcium acetate and vitamin D once a day;the control group was taking alendronate sodium tablets.The preventive effects,LBOS score of low back pain and the occurrence of adverse reactions were compared between the two groups.Results The preventive effect of the treatment group was(95.83%),which was significantly better than that of the control group(75.00%)(χ^2=16.941,P<0.01);the LBOS score of the treatment group after treatment was(60.4±11.9)points,which was significantly higher than the control(55.6±10.8)points in the group(t=2.720,P<0.01);the occurrence of various adverse reactions in the treatment group was less than that in the control group(P<0.05).Conclusion Calcium acetate and vitamin D can effectively increase the bone mineral density and improve the clinical symptoms of elderly patients with osteoporosis,and have good safety.

关 键 词：醋酸钙 维生素D 骨质疏松症 预防效果 

分 类 号：R580[医药卫生—内分泌]