清热利尿通淋方治疗非淋菌性尿道炎疗效及对相关因子的影响  

The effect of Qingre Liniao Tonglin recipe for treating patients with non gonococcal urethritis and its influence on the related factors

作　　者：石永柱 陈如 马锋 SHI Yongzhu;CHEN Ru;MA Feng(321 Hospital, Hanzhong, Shaanxi Province, 723000)

机构地区：[1]三二〇一医院,汉中723000

出　　处：《中国计划生育学杂志》2020年第8期1226-1229,共4页Chinese Journal of Family Planning

摘　　要：目的:探讨中医清热利尿通淋方辅助西医治疗非淋菌性尿道炎的效果及对相关炎性因子水平的影响。方法:选取本院诊治的非淋菌性尿道炎患者200例,随机分为两组各100例,两组均给予西医抗生素基础药物治疗,观察组同时服用中医清热利尿通淋方辅助治疗2周;对比两组治疗前后临床症状评分、血清白细胞介素-2(IL-2)、IL-4、IL-8,比较两组临床疗效。结果:治疗后观察组患者的尿频、尿痛、尿急、尿道刺痒、尿道口分泌物和小便黄赤评分均低于对照组,血清IL-2(103.2±11.0 ng/L)、IL-4(128.5±26.4 ng/L)、IL-8(75.1±16.3 ng/L)水平均低于对照组(114.2±13.5 ng/L、143.2±28.1 ng/L、86.6±18.5 ng/L),临床总有效(95.8%)高于对照组(92.9%)(均P<0.05)。结论:中医清热利尿通淋方辅助西医疗法治疗非淋菌性尿道炎的效果优于单纯西医疗法,且降低了患者炎性因子水平。Objective:To explore the effect of Qingre Liniao Tonglin recipe for treating patients with non gonococcal urethritis,and to study its influence on the related factors.Methods:200 patients with non gonococcal urethritis were selected and were randomly divided into two groups(100 cases in each group).The patients in the two groups were all given western medicine antibiotics,and patients in the experimental group were given Chinese medicine Qingre Liniao Tongling recipe for 2 weeks additionally.The clinical symptom scores,and the levels of serum IL-2,IL-4 and IL-8 before and after treatment,and the clinical efficacy of patients were compared between the two groups.Results:After treatment,the rates of urinary frequency,dysuria,urinary urgency,urinary tract pruritus,and urethral secretion,and the score of yellow and red of urine of patients in the experimental group were significant lower than those of patients in the control group.After treatment,the serum IL-2,IL-4 and IL-8 levels of patients in the experimental group were 103.2±11.0 ng/L,128.5±26.4 ng/L,and 75.1±16.3 ng/L,respectively,which were significant lower than those(114.2±13.5 ng/L,143.2±28.1 ng/L,and 86.6±18.5 ng/L,respectively)of patients in the control group,but the total clinical efficacy of the patients in the experimental group was 95.8%,which was significant lower than that(92.9%)of patients in the control group(all P<0.05).Conclusion:The effect of Chinese medicine Qingre Liniao Tonglin recipe combined with Western medicine for treating patients with non gonococcal urethritis is better than that of Western medicine used only,which can reduce the levels of inflammatory factor of patients.

关 键 词：非淋菌性尿道炎 清热利尿通淋方 炎性因子 

分 类 号：R69[医药卫生—泌尿科学]