黄羽肉鸡感染火鸡组织滴虫后血清生化指标的动态变化  

Dynamic Changes of Biochemical Indexes in Yellow-feather Broilers Infected with H.meleagridis

作　　者：禚振男 孔令明 王子静 郭平[1,2] 曲昌宝 刘丹丹[1,2] 钱晨 陶建平[1,2] 许金俊 ZHUO Zhennan;KONG Lingming;WANG Zijing;GUO Ping;QU Chanbao;LIU Dandan;QIANG Chen;TAO Jianping;XU Jinjun(College of Veterinary Medicine,Yangzhou University,Yangzhou,Jiangsu 225009;Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses,Yangzhou,Jiangsu 225009;Animal Husbandry and Veterinary Administration of Zhucheng City,Zhucheng,Shandong 262200)

机构地区：[1]扬州大学兽医学院,江苏扬州225009 [2]江苏高校动物重要疫病与人兽共患病防控协同创新中心,江苏扬州225009 [3]山东省诸城市畜牧业发展中心,山东诸城262200

出　　处：《中国家禽》2020年第8期30-34,共5页China Poultry

基　　金：国家自然科学基金面上项目(31772727);扬州市重点研发计划(现代农业)项目(YZ2017051);江苏高校优势学科建设二期工程资助项目;扬州大学“青蓝工程”资助项目(2018年度);扬州大学专业学位研究生实践创新计划项目(XSJCX18_075)。

摘　　要：为了进一步从病理生理角度探究火鸡组织滴虫的致病机理,通过火鸡组织滴虫JSYZ-A株泄殖腔感染15日龄苏禽黄羽肉鸡,感染后7~31 d,每3天采集非抗凝血进行常规生化指标的测定。结果显示:火鸡组织滴虫的感染会导致感染鸡增重缓慢,谷丙转氨酶、谷草转氨酶、谷氨酰胺转移酶、球蛋白含量不同程度上升,尿素氮、葡萄糖含量下降,甘油三酯浓度先升后降,而其他生化指标无明显异常。肝脏是火鸡组织滴虫入侵的主要靶器官,其功能受到广泛损伤,是导致鸡群发病、增重下降和死亡的主要原因。研究结果为火鸡组织滴虫致病机理的阐明和组织滴虫病的药物防治提供了一定的参考依据。In order to explore the mechanism of pathogenicity of H.meleagridis at pathophysiological level,15-day-age yellow-feather broilers were cloacally infected with JSYZ-A strain.At 7 to 31 days post-infection,biochemical indexes of serum were analyzed every three days.The results indicated that H.meleagridis infection could cause weight lose,decrease the level of blood urea nitrogen and glucose,increase the level of alanine aminotransferase,aspartate aminotransferase,gamma-glutamyltransferase,and globulin.Liver was the main target organ of this parasite,and its function had been extensively damaged,which was the main cause of chicken death.The results provided a reference for the mechanism of pathogenicity of H.meleagridis and treatment of histomoniasis with drugs.

关 键 词：火鸡组织滴虫 生化指标 增重 鸡 

分 类 号：S852.65[农业科学—基础兽医学]