温针对神经根型颈椎病患者SF-MPQ量表、细胞因子影响研究  

Study on Effect of Warm Needling on SF-MPQ and Cytokines in Patients with Cervical Spondylosis of Nerve Root Type

作　　者：任长辉 李红兵[1] REN Changhui;LI Hongbing(Langzhong Hospital of Traditional Chinese Medicine, Langzhong 637400, China)

机构地区：[1]四川省阆中市中医院,四川阆中637400

出　　处：《针灸临床杂志》2020年第8期45-48,共4页Journal of Clinical Acupuncture and Moxibustion

摘　　要：目的:研究温针对神经根型颈椎病患者简化McGill疼痛问卷(SF-MPQ)、细胞因子变化的影响。方法:选取我院2016年3月—2018年5月收治的神经根型颈椎病患者118例,分为两组。对照组给予推拿、牵引、消炎镇痛和营养神经等常规治疗,观察组在常规治疗基础上给予温针治疗,分析两组患者治疗后的临床疗效。结果:观察组疼痛消失时间(8.69±1.25)d、活动受限消失时间(10.56±2.04)d、头晕消失时间(8.56±1.30)d短于对照组(P<0.05)。两组治疗前核因子-κB(NF-κB)、白细胞介素-8(IL-8)、白细胞介素-10(IL-10)水平组间比较,差异无统计学意义(P>0.05);观察组治疗后IL-10水平高于对照组,NF-κB、IL-8水平低于对照组(P<0.05)。两组治疗前SF-MPQ量表评分组间比较,差异不具有统计学意义(P>0.05);观察组治疗后视觉模拟定级法(VAS)评分、现有疼痛强度(PPI)评分、疼痛分级指数(PRI)低于对照组(P<0.05)。观察组1年后复发率6.78%(4/59),低于对照组的20.34%(12/59),差异具有统计学意义(P<0.05)。结论:温针应用于神经根型颈椎病患者可调节NF-κB、IL-10和IL-8的含量,抑制炎症反应,改善疼痛等临床症状,且复发率低。Objective:To study warm needling on the changes of simplified McGill pain questionnaire(SF-MPQ)and cytokines in patients with cervical spondylosis of nerve root type.Methods:118 patients with cervical spondylosis of nerve root type were randomly divided into the control group and the observation group.The control group was treated with conventional therapies,such as tuina,traction,medications of anti-inflammatory analgesia and neurotrophy;on which basis,the observation group was also treated with warm needling.The clinical effect was assessed in the two groups.Results:The disappearance time of pain,activity limitation and dizziness were(8.69±1.25)d,(10.56±2.04)d and(8.56±1.30)d respectively in the observation group,which were shorter than those in the control group(P<0.05).There were no significant differences in the levels of NF-κB,IL-8 and IL-10 between the two groups before the treatment(P>0.05).After the treatment,the level of IL-10 was higher and the levels of NF-κB and IL-8 were lower in the observation group than those in the control group(P<0.05).There was no significant difference in SF-MPQ between the two groups(P>0.05).After the treatment,the scores of VAS,PPI and PRI were lower in the observation group than those in the control group(P<0.05).The recurrence rate one year after the treatment was 6.78%(4/59)in the observation group,which was lower than 20.34%(12/59)in the control group(P<0.05).Conclusion:Warm needling can regulate the contents of NF-κB,IL-10 and IL-8,inhibit inflammatory reactions,improve pain and other clinical symptoms in patients with cervical spondylosis of nerve root type with low recurrence rate.

关 键 词：神经根型 颈椎病 温针 简化McGill疼痛问卷 核因子-ΚB 

分 类 号：R246.2[医药卫生—针灸推拿学]