膳食含糖饮料摄入与高尿酸血症关系的研究进展  

Research progress on the relationship between the intake of dietary sugar-sweetened beverage and hyperuricemia

作　　者：孙艺菲 徐昕[1] 赵欢 吴茜 白佳佳 赵玉虹[1] SUN Yi-fei;XU Xin;ZHAO Huan;WU Xi;BAI Jia-jia;ZHAO Yu-hong(Shengjing Hospital of China Medical University,Shenyang,Liaoning 110004,China)

机构地区：[1]中国医科大学附属盛京医院,辽宁沈阳110004

出　　处：《现代预防医学》2020年第17期3113-3116,共4页Modern Preventive Medicine

基　　金：国家重点研发计划精准医学研究重点专项(2017YFC0907400)。

摘　　要：目的探究膳食含糖饮料摄入与高尿酸血症的关系。方法以含糖饮料、果糖、高尿酸血症和尿酸为检索词在中国知网,PubMed和Web of Science数据库上检索发表于2019年10月29日之前的相关文章。并对检索的文章进行严格地筛查,以获得相关文章。结果经过检索一共检索到2493篇文献,将重复文献与非相关研究排除后,对剩余的30篇文章进行全文阅读,最终有9篇文章被纳入。其中有包括6篇国外的研究和3篇国内的研究。我们对这9篇文章进行了阐述,并对含糖饮料与高尿酸血症相关的可能机制进行了探究。结论有研究显示膳食含糖饮料摄入与高尿酸血症之间存在正相关关系,然而还有部分研究未发现膳食含糖饮料摄入与高尿酸血症相关,且缺乏纵向研究。因此还需要进一步的研究。Objective To explore the relationship between dietary intake of sugary beverage and hyperuricemia.Methods China National Knowledge Infrastructure,PubMed and Web of Science weresearched for published relevant papers from inception to October 10,2019 by using sugar-sweetened beverages,fructose,hyperuricemia and uric acid as search words.And the retrieved articles were screened strictly to obtain relevant articles.Results After search,a total of 2493 articles were retrieved.After duplicate articles and irrelevant studies were excluded,the leaving 30 articles were read in full,and 9 articles were finally included,including 6 foreign studies and 3 domestic studies.We expounded on these 9 articles and explored the possible mechanisms of hyperuricemia associated with sugary beverages.Conclusion Some studies have shown that there is a positive correlation between dietary sugar-sweetened beverage consumption and hyperuricemia,however,some other studies have not found a relationship between them,and longitudinal studies are lacking.Thus,further research is needed.

关 键 词：含糖饮料 高尿酸血症 尿酸 果糖 

分 类 号：R589.7[医药卫生—内分泌]