1285例耳鼻喉患者大便菌群比失调状况调查  

Investigation ondysbiosis of fecal flora ratio in 1285 ENT patients

作　　者：胡秀娟[1] 陈静[1] 魏雪梅 兰德 曾甦漪[1] 张杰[1] 康伟 Hu Xiujuan;Chen Jing;Wei Xuemei;Lan De;Zeng Suyi;Zhang Jie;Kang Wei(Otolaryngology&Head and Neck Surgery,Affiliated Hospital of Chendu University,Chengdu,Sichuan 610081,China)

机构地区：[1]成都大学附属医院耳鼻咽喉头颈外科,四川成都610081

出　　处：《现代临床医学》2020年第5期348-350,357,共4页Journal of Modern Clinical Medicine

基　　金：四川省医学科研青年创新课题(Q14003)。

摘　　要：目的:调查耳鼻喉常见病患者的大便球/杆菌比例(简称"大便菌群比")情况,探讨耳鼻喉科疾病与肠道菌群的关系。方法:选取我院1285例耳鼻喉患者,统计不同性别、年龄及病种的大便菌群比失调率,分别按>3∶7和>5∶5的标准对失调率前5位疾病和前3位年龄组排序。结果:以大便菌群比>3∶7的标准,失调率前5位疾病分别为变应性鼻-鼻窦炎、阻塞性睡眠呼吸暂停低通气综合征、儿童腺样体扁桃体肥大、头颈良性肿物、鼻出血,前3位的人群为幼儿组、成年后期组、青年组;以大便菌群比>5∶5的标准,失调率前5位疾病分别为儿童腺样体扁桃体肥大、头颈恶性肿瘤、耳内科疾病、慢性扁桃体炎、变应性鼻-鼻窦炎,前3位的人群为幼儿组、成年早期组、老年组。结论:大便菌群比失调在耳鼻喉患者中较为普遍,不同年龄组差异明显,其中幼儿人群的变应性鼻-鼻窦炎和儿童腺样体扁桃体肥大与肠道菌群失调关系最为紧密。Objective:To investigate the ratio of fecal coccus to bacillus(hereinafter referred to as"fecal flora ratio")in patients with common diseases of(ear,nose and throat)ENT,and to explore the relationships between otorhinolaryngological diseases and intestinal flora.Methods:1285 ENT patients of our hospital were selected,and the dysbiosis rate of fecal flora ratio in different genders,ages and diseases were counted.The top five diseases and the top three age groups were ranked according to the standards of more than 3∶7 and more than 5∶5,respectively.Results:According to the standard of fecal flora ratio more than 3∶7,the top five diseases of dysbiosis rate were allergic rhinosinusitis,obstructive sleep apnea-hypopnea syndrome,adenotonsillar hypertrophy in children,benign tumor of head and neck,and epistaxis;the top three age groups were early childhood group,late adulthood group and youth group.According to the standard of fecal flora ratio more than 5∶5,the top five diseases of dysbiosis rate were adenotonsillar hypertrophy in children,malignant tumor of head and neck,otology diseases,chronic tonsillitis and allergic rhinosinusitis;the top three age groups were early childhood group,early adulthood group and elderly group.Conclusion:The dysbiosis of fecal flora ratio is common in ENT patients,and there are significant differences among different age groups.Allergic rhinosinusitis and adenotonsillar hypertrophy in children are closely related to intestinal flora imbalance.

关 键 词：耳鼻喉 常见病 大便菌群比 失调 

分 类 号：R857.76[医药卫生—航空、航天与航海医学]