家庭聚集性肺炎支原体肺炎与家庭聚集性新型冠状病毒肺炎临床及影像学分析  

Comparison of clinical and imaging analysis on family-aggregated Mycoplasma pneumonia and COVID-19

作　　者：甘川[1] 刘润宁[2] 付海军 王成秀[4] 徐新献[5] 李茜[6] Gan Chuan;Liu Running;Fu Haijun;Wang Chengxiu;Xu Xinxian;Li Qian(Department of Infection,Children's Hospital of Chongqing Medical University/Ministry of Education Key Laboratory of Child Development and Disorders/National Clinical Research Center for Child Health and Disorders/China International Science and Technology Cooperation Base of Child Development and Critical Disorders/Chongging Key Laboratory of Pediatrics;Department of Child Healthcare,The Fifth People's Hospital of Chongqing/Chongqing Renji Hospital,University of Chinese Academy of Sciences;Department of Radiology,The Fifth People's Hospital of Chongqing/Chongqing Renji Hospital,University of Chinese Academy of Sciences;Department of Pediatrics,The Fifth People's Hospital of Chongqing/Chongqing Renji Hospital,University of Chinese Academy of Sciences;Department of General Medicine,The Fifth People's Hospital of Chongqing/Chongqing Renji Hospital,University of Chinese Academy of Sciences;Deparlment of Infectious Diseases,The Fifth People's Hospital of Chongqing/Chongqing Renji Hospital,University of Chinese Academy of Sciences)

机构地区：[1]重庆医科大学附属儿童医院感染科儿童发育疾病研究教育部重点实验室国家儿童健康与疾病临床医学研究中心儿童发育重大疾病国家国际科技合作基地儿科学重庆市重点实验室,重庆400014 [2]重庆市第五人民医院(中国科学院大学重庆仁济医院)儿童保健科,重庆400062 [3]重庆市第五人民医院(中国科学院大学重庆仁济医院)放射科,重庆400062 [4]重庆市第五人民医院(中国科学院大学重庆仁济医院)儿科,重庆400062 [5]重庆市第五人民医院(中国科学院大学重庆仁济医院)全科医学科,重庆400062 [6]重庆市第五人民医院(中国科学院大学重庆仁济医院)感染性疾病科,重庆400062

出　　处：《重庆医科大学学报》2020年第7期1008-1010,共3页Journal of Chongqing Medical University

摘　　要：目的:分析家庭聚集性肺炎支原体(Mycoplasma pneumonia,MP)肺炎与家庭聚集性新型冠状病毒肺炎(coronavirus disease 2019,COVID-19)的临床特点、外周血细胞及胸部CT。方法:通过对家庭聚集性MP肺炎、家庭聚集性COVID-19临床表现、外周血细胞、CT结果比较,了解两者之间的异同。结果:MP肺炎好发于低年龄段,干咳、发热为主要临床表现,常伴有咽痛;胸部CT从肺门向外延伸肺野、累及多个肺叶并易实变。COVID-19好发于高年龄段,有基础疾病者并发症较多,发热为主要表现,常伴有干咳、精神萎靡、胸痛、胸闷,胸部CT主要累及肺的外周,毛玻璃影多见。两者外周血细胞对比,白细胞计数(white blood cell count,WBC)、淋巴细胞绝对值、中性粒细胞绝对值、血红蛋白(hemoglobin,Hb)、血小板计数(platelet count,PLT)及C反应性蛋白(C-reactive protein,CRP)无统计学差异(均P>0.05);消化道症状比较少见;均可伴乏力。结论:家庭聚集性MP肺炎与家庭聚集性COVID-19在临床、外周血细胞及影像学表现上存在诸多相似之处,临床容易误诊,及早的病原学检查有助于早期诊断。Objective:To analyze the clinical characteristics,peripheral blood cells and chest CT of family aggregated Mycoplasma pneumonia(MP)pneumonia and family-aggregated coronavirus disease 2019(COVID-19).Methods:The clinical manifestations,peripheral blood cells and CT results of family-aggregated MP pneumonia and family-aggregated COVID-19 were compared to comprehend the similarities and differences.Results:MP pneumonia tended to occur in the younger age group,with main manifestations of dry cough and fever,often accompanied by pharyngalgia.Chest CT showed that the pneumonia was extended the lung field from the hilum to the outside,involved multiple lobes and easily consolidated.However,COVID-19 tended to occur in the older age group.Patients with underlying diseases were more likely to have complications and fever was the main manifestation,often accompanying dry cough,depression,chest pain and chest tightness.Chest CT showed that it mainly involved the peripheral lung and ground glass opacities.WBC,absolute lymphocyte,absolute neutrophil,Hb,PLT and CRP between two groups(all P values were greater than 0.05)had no significant differences;digestive tract symptoms were relatively rare;weakness was going to accompanied with all symptoms.Conclusion:There are many similarities between family-aggregated MP pneumonia and family-aggregated COVID-19 in the clinical,peripheral blood cells and imaging manifestations,which are easy to be misdiagnosed,and early etiological examination is helpful for early diagnosis.

关 键 词：肺炎支原体 新型冠状病毒肺炎 家庭聚集性 

分 类 号：R518.9[医药卫生—内科学]