早期液体疗法对ICU围手术期高乳酸血症患者的意义  

Significance of Early Fluid Therapy in ICU Patients with Perioperative Hyperlactic Academia

作　　者：张芸[1] 祁恒旭[2] 郭玉梅[1] 曹勇[1] 田春晖 ZHANG Yun;QI Hengxu;GUO Yumei;CAO Yong;TIAN Chunhui(Department of Emergency ICU,Dalian Central Hospital,Dalian 116000,China;Department of Neurology,Dalian Central Hospital,Dalian 116000,China)

机构地区：[1]大连市中心医院急诊ICU,辽宁大连116000 [2]大连市中心医院神经内科,辽宁大连116000

出　　处：《中国医药指南》2020年第24期71-72,共2页Guide of China Medicine

摘　　要：目的探讨早期液体疗法对ICU围手术期高乳酸血症患者的意义。方法选取2018年1月至2019年1月在大连市中心医院急诊ICU以及神经内科的80例ICU围手术期高乳酸血症患者,随机分为试验组和对照组,每组40例。对照组患者采取常规液体治疗,试验组患者采用早期液体治疗。监测两组患者进入ICU后6、24、48 h的乳酸值以及液体入量等指标,并评价两种液体治疗方案的优劣。结果试验组患者进入ICU后6、24 h乳酸水平分别为(1.86±2.20)、(1.65±1.40)mmol/L,对照组分别为(2.41±3.20)、(1.99±1.60)mmol/L,差异均有统计学意义(均P <0.05);试验组患者进入ICU后48 h乳酸水平为(1.42±2.50)mmol/L,对照组为(1.44±2.20)mmol/L,差异无统计学意义(P> 0.05)。试验组患者进入ICU后6 h的液体入量显著多于对照组,差异有统计学意义(P <0.05);两组患者进入ICU后24、48 h的液体入量比较,差异均无统计学意义(均P> 0.05)。结论早期液体疗法可改善ICU围手术期患者的高乳酸血症,提升患者的治疗效果。Objective To investigate the signifi cance of early fl uid therapy in ICU patients with perioperative hyperlactic acid.Methods From January 2018 to January 2019,80 cases of perioperative hyperlactic acid patients in the Department of Emergency ICU and Neurology,Dalian Central Hospital were randomly divided into experimental group and control group,with 40 cases in each group.The patients in the control group were treated with conventional liquid therapy,the patients in the experimental group were treated with early liquid therapy.By monitoring the lactic acid values at 6,24 and 48 h after admission to ICU and the superiority of the two liquid treatment schemes was evaluated.Results The lactic acid level of the experimental group was(1.86±2.20)mmol/L at 6 h and(1.65±1.40)mmol/L at 24 h,while that of the control group were(2.41±3.20)mmol/L and(1.99±1.60)mmol/L,the diff erences were statistically signifi cant(all P<0.05).The lactic acid level was(1.42±2.50)mmol/L at the 48 h of the experimental group,and was(1.44±2.20)mmol/L in the control group,there was no statistically significant difference(P>0.05).The liquid intake of the experimental group was significantly higher than the control group at 6 h,and the difference was statistically significant(P<0.05).The liquid intake of the two groups at 24,48 h were not signifi cant diff erence(all P>0.05).Conclusion Early liquid therapy can improve the perioperative hyperlactic acidemia in ICU patients,and improve the treatment eff ect of patients.

关 键 词：高乳酸血症 液体疗法 围手术期 乳酸水平 液体入量 

分 类 号：R631.2[医药卫生—外科学]