1型糖尿病患者孕前管理现状与需求分析  

The current status of preconception care among women with type 1 diabetes mellitus and needs assessment

作　　者：王超凡 骆斯慧 杨黛稚[1] 严晋华[1] 许雯[1] 姚斌[1] 翁建平 郑雪瑛[1] Wang Chaofan;Luo Sihui;Yang Daizhi;Yan Jinhua;Xu Wen;Yao Bin;Weng Jianping;Zheng Xueying(Department of Endocrinology and Metabolism,the Third Affiliated Hospital of Sun Yat-sen University,Guangdong Diabetes Prevention and Control Research Center,Guangdong Provincial Key Laboratory of Diabetology,Guangzhou 510630,China;Department of Endocrinology,the First Affiliated Hospital of University of Science and Technology of China(Anhui Provincial Hospital),Hefei 230001,China)

机构地区：[1]中山大学附属第三医院内分泌与代谢病学科广东省糖尿病防治研究中心广东省糖尿病防治重点实验室,广州510630 [2]中国科学技术大学附属第一医院(安徽省立医院)内分泌科,合肥230001

出　　处：《中华糖尿病杂志》2020年第8期593-599,共7页CHINESE JOURNAL OF DIABETES MELLITUS

基　　金：广东省基础与应用基础研究基金(2019A1515010979);广东省省级科技计划项目(2018A070701019);中央高校基本科研业务费专项资金资助(WK9110000137);国家卫计委公益性行业科研基金项目(201502011);世界糖尿病基金会项目(WDF 14-921)。

摘　　要：目的调查我国1型糖尿病(T1DM)患者孕前管理(PCC)现状与需求。方法从2016年12月至2018年1月在T1DM管理应用软件“糖糖圈®”形成的患者社区中招募14岁及以上的T1DM女性患者进行问卷调查,收集患者一般情况、PCC现状与需求等资料。相关分析采用Spearman相关分析,采用Wilcoxon秩和检验进行数据比较。结果共收到来自全国28省市有效问卷386份。72.8%(281/386)患者年龄在21~35岁,25.4%(98/386)患者糖化血红蛋白>7.5%,有妊娠经历的患者中48.8%(62/127)曾有过不良妊娠结局。仅12.4%(48/386)患者比较了解妊娠相关知识,了解程度与患者学历呈正相关(rs=0.162,P<0.01)。72.6%(280/386)患者表示实际就诊中和医生沟通时间不足10 min,明显低于理想沟通时间(Z=-14.109,P<0.01)。86.0%(332/386)患者因T1DM影响异性交往及结婚生育。结论我国T1DM女性患者PCC的健康需求亟待解决。加强对T1DM患者的专业支持及社会支持将有助于提高T1DM患者PCC参与率,减轻患者心理负担。Objective To investigate the current status of preconception care(PCC)among Chinese women with type 1 diabetes mellitus(T1DM)and assess their needs.Methods An online questionnaire survey was conducted from December 2016 to January 2018 in the patient community consisted of users of TangTangQuan®,a mobile application dedicated for the management of T1DM.We recruited women with T1DM who aged 14 year and elder.Data including the basic information of women with T1DM,their perspectives on current status of PCC and their needs were collected.Spearman correlation analysis was used in correlation analysis and Wilcoxon rank sum test was used to compare the differences.Results A total of 386 valid responses were received at the end of the survey,which covered 28 provinces of China.Among the participants of the survey,72.8%(281/386)were aged 21 to 35 years and 25.4%(98/386)had glycated hemoglobin A1c>6.5%,while 48.8%(62/127)who experienced pregnancy had been confronted with adverse pregnancy outcomes.Only 12.4%(48/386)of the participants thought they had sufficient knowledge on PCC,and their educational background correlated positively with the knowledge degree(rs=0.162,P<0.01).72.6%(280/386)reported less than 10 min per visit to the doctor,significantly shorter than their ideal time for full communication(Z=-14.109,P<0.01).86.0%(332/386)expressed that T1DM impacted on their relationship,marriage and childbearing.Conclusion There is an urgent need for Chinese women with T1DM to receive PCC.It will be helpful for women with T1DM to facilitate the participation in PCC and relieve their psychological burden by enhancing professional and social support for them.

关 键 词：糖尿病 1型 孕前管理 问卷调查 

分 类 号：R587.1[医药卫生—内分泌]