磁共振弥散频谱成像原理及其在神经系统的研究进展  

Research progress of magnetic resonance diffusion spectrum imaging in the nervous system

作　　者：宫智波 陈宏海[1] 刘书峰[1] 沙琳[1] GONG Zhibo;CHEN Honghai;LIU Shufeng;SHA Lin(Department of Radiology,the Second Hospital of Dalian Medical Unversity,Dalian 116000,China)

机构地区：[1]大连医科大学附属第二医院放射科,大连116000

出　　处：《磁共振成像》2020年第9期809-812,816,共5页Chinese Journal of Magnetic Resonance Imaging

基　　金：本科生导师制在影像技术专业实习中的应用与评价基金(编号:DYLX18020)。

摘　　要：弥散频谱成像技术(diffusion spectrum imaging,DSI)是一种新型的用来探究人体纤维走行的弥散成像技术,能够真实准确地将颅内交叉环绕以及走行复杂的纤维束可视化,弥补了其他弥散成像技术的不足,并且通过DSI相关参数可判断纤维组织损伤程度,对于描绘组织微观结构具有极大优势。该文介绍弥散频谱成像的成像原理及其参数,同时介绍DSI对于人体解剖结构以及引起临床疾病的脑白质纤维结构变化的显示,有助于对中枢神经系统疾病病理生理的研究,同时有助于临床疾病的诊断与治疗。Diffusion spectrum imaging(DSI)is an advanced diffusion imaging technology used to describe the fiber tracts profile of the human body.It can truly and accurately visualize intracranial intersecting and complex fiber tracts,which made up for other diffusion imaging's shortcomings.And the degree of fiber tracts damage can be estimated through the use of DSI-related parameters.The two characteristics have great advantages in describing the microstructure of the tissue.This article introduces the fundamental principle of DSI and parameters of diffusion spectrum imaging,and also reveals central nervous system anatomy details and the changes in the white matter fiber structure that cause clinical diseases accroding to DSI.It is helpful for the study of the pathophysiology of central nervous system diseases and also provides more options for diagnosis and treatment of diseases.

关 键 词：弥散频谱成像 中枢神经系统 

分 类 号：R445.2[医药卫生—影像医学与核医学] R816.1[医药卫生—诊断学]