Crystal structure of the African swine fever virus structural protein p35 reveals its role for core shell assembly  

作　　者：Guobang Li Dan Fu Guangshun Zhang Dongming Zhao Mingyu Li Xue Geng Dongdong Sun Yuhui Wang Cheng Chen Peng Jiao Lin Cao Yu Guo Zihe Rao 

机构地区：[1]State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy,Nankai University,Tianjin 300350,China [2]State Key Laboratory of Veterinary Biotechnology,Harbin Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Harbin 150001,China [3]School of Life Sciences,Tianjin University,Tianjin 300071,China

出　　处：《Protein & Cell》2020年第8期600-605,共6页蛋白质与细胞（英文版）

摘　　要：Dear Editor,The African swine fever(ASF)is a highly contagious hemorrhagic and lethal disease in domestic pigs.The ASF outbreaks of in many Asia countries,including China,Vietnam,Mongolia,and South Korea,have posed a huge threat to the pig indusry.In the attempt to stop ASF from spreading further in China's Mainland,more than 10 million pigs have been culled since August 2018.The causative agent for ASF is a DNA virus,African swine fever virus(ASFV).Although this deadly disease has been reported in Kenya nearly one hundred years ago,there has been no vaccine for protection from ASFV infection or effective treatments to cure ASF until now.

关 键 词：SWINE FEVER AFRICAN 

分 类 号：S852.651[农业科学—基础兽医学]