临床药师参与诊治1例儿童药物性肝损伤的实践体会  

Participation of Clinical Pharmacists in the Diagnosis and Treatment for Drug-Induced Liver Injury in Children

作　　者：袁勇 戴志凌[2] 付燕[1] Yuan Yong;Dai Zhiling;Fu Yan(Kunming City Maternal and Child Health Hospital,Yunnan Kunming 650000,China;The Second Affiliated Hospital of Kunming Medical University,Yunnan Kunming 650000,China)

机构地区：[1]昆明市妇幼保健院,云南昆明650000 [2]昆明医科大学第二附属医院,云南昆明650000

出　　处：《儿科药学杂志》2020年第9期42-45,共4页Journal of Pediatric Pharmacy

摘　　要：目的:探讨临床药师在儿童药物性肝损伤(DILI)诊治过程中的药学监护。方法:临床药师通过Roussel Uclaf因果关系(RUCAM)评估量表对1例DILI患儿进行因果关系分析,结合指南及循证证据,调整DILI的治疗方案,控制患儿病情发展。结果:通过药学服务实践,临床药师协助医师优化了治疗方案,患儿肝功能恢复正常。结论:临床药师的参与对儿童DILI的判断、治疗具有积极意义。Objective:To probe into the pharmaceutical care for the diagnosis and treatment of drug-induced liver injury(DILI)in children by clinical pharmacists.Methods:Clinical pharmacists used Roussel Uclaf(RUCAM)evaluation scale to analyze the causal relationship of DILI in a child,adjust the treatment of DILI according to the guidelines and evidence-based evidence,and control the development of the disease.Results:Through the practice of pharmaceutical care,clinical pharmacists assisted clinicians in optimizing the treatment plan,and the biochemical indexes of liver function nearly recovered.Conclusion:The participation of clinical pharmacists has positive significance for the judgment and treatment of children with DILI.

关 键 词：药物性肝损伤 因果分析 糖皮质激素 临床药师 

分 类 号：R969.3[医药卫生—药理学]