4D数字脑图谱的构建、不对称性及遗传倾向  

The construction, asymmetry and genetic correlation of 4D digital brain atlas

作　　者：刘树伟 娄云霞[1,2] 汤煜春 LIU Shuwei;LOU Yunxia;TANG Yuchun(Research Center for Sectional and Imaging Anatomy,Cheeloo College of Medicine,Shandong University,School of Basic Medical Sciences,Shandong University,Digital Human Institute,Shandong University,Jinan 250012,Shandong,China;Institute of Brain and Brain-Inspired Science,Shandong University,Jinan 250012,Shandong,China)

机构地区：[1]山东大学齐鲁医学院断层影像解剖学研究中心,山东大学基础医学院,山东大学数字人研究院,山东济南250012 [2]山东大学脑与类脑科学研究院,山东济南250012

出　　处：《山东大学学报（医学版）》2020年第8期28-33,共6页Journal of Shandong University:Health Sciences

基　　金：国家自然科学基金(81371533,31771328);山东省重点研发计划(2017CXGC1501)。

摘　　要：人脑图谱是研究大脑结构和功能的基本工具,是进行脑结构和功能信息分析处理的重要手段。构建不同年龄段、不同性别、不同颅脑分型的标准化4D脑图谱,并利用计算机技术进行可视化和大脑结构的动态分析,可以为人脑结构和功能的发育及发展变化提供详实的形态学基础。概述4D数字脑图谱的构建、不对称性及其遗传倾向,并对未来的研究方向进行展望。Human Brain Mapping is an important tool for exploring the structure and function of human brains,and is the basic platform for analyzing and processing brain structure and function information.The establishment of standardized 4 D brain maps of different ages,genders and brain types,and the use of computer technology for visualization and dynamic analysis of brain structure can provide a detailed morphological basis for the embryogenesis and development of human brain structure and function.In this review,we present recent studies regarding the construction,asymmetry and genetic correlation of 4 D digital brain atlas.Finally,discussions on the future research directions of brain atlas are given.

关 键 词：数字化 脑图谱 脑模板 不对称性 遗传倾向 

分 类 号：R338.1[医药卫生—人体生理学]